麻豆传媒

I am an NHIP Senior Clinical Fellow and Honorary Consultant based in the Translational and Clinical Research Institute at 麻豆传媒 within the Immunity and Inflammation theme. Clinically I work as a consultant in Paediatric Respiratory Medicine at the Great North Children's Hospital and the Freeman Hospital in 麻豆传媒 upon Tyne where I work within the regional Paediatric Cystic Fibrosis and Sleep Services. I also have a general respiratory clinic where I see patients with a range of respiratory conditons.

My academic interests involve research investigating abnormal airway epithelial physiology in children who have chronic respiratory diseases such as cystic fibrosis.

Previous positions

• NIHR Clinical Lecturer, 麻豆传媒 (2019-2022)
• Clinical Research Associate, 麻豆传媒 (2015-2018)
• Paediatric Specialty Trainee, Northern Deanery, 麻豆传媒 (2010-2019)

Qualifications

MBBS, MRes, MRCPCH, PhD 

Roles and responsibilities

CF Trust Standards of Care Working Group (2023 -)

NIHR Reviewer Development Scheme (2020 to present)

UK Cystic Fibrosis Medical Association Paediatric Trainee Representative (2019 to present)

麻豆传媒 Ethics Committee Reviewer (2019 to present)

Editorial board member ‘Beat Asthma’ online resource (2017)

ALSG Newborn Life Support Instructor (2015 to present)

I am an NIHR ACL in Paediatric Respiratory Medicine and my research interests in cystic fibrosis and the development of relevant airway models to investigate the impact of dysfunctional airway epithelial ion transport and physiology in the cystic fibrosis airway. 

During my Wellcome Trust funded Clinical Research Training Fellowship I investigated the role of the alternative chloride channel, TMEM16A, as a therapeutic target for cystic fibrosis. During this PhD, I utilised differentiated primary airway epithelial cell culture models derived from children and applied these models to investigate ion transport using electrophysiological techniques. Since my PhD, I have been able to further my research within this field to further investigate abnormal ion transport processes in individuals with cystic fibrosis and how these vary within the nasal and bronchial airways. I was awarded an Academy of Medical Sciences Starter Grant during my NIHR Clinical Lectureship to continue this work.

Awards

Academy of Medical Sciences Starter Grant for Clinical Lecturers (awarded 2021)

Wellcome Trust Institutional Strategic Support Fund (awarded 2019)

Wellcome Trust ISSF Broadening Our Horizons Scheme, North American Cystic Fibrosis Conference (awarded 2019)

Wellcome Trust Clinical Research Training Fellowship (awarded 2016)

British Paediatric Respiratory Society Travel Award, European Cystic Fibrosis Society Conference (awarded 2019)

In my clinical work, I am involved in teaching medical students and doctors in aspects of paediatrics and paediatric respiratory medicine. I am also a certified ALSG Newborn Life Support Instructor.

I have supervised students within the university including during summer studentships, undergraduate and postgraduate projects.

I am actively involved in structured teaching specifically with the undergraduate Biomedical Sciences and Physiology degree programmes.

I am also a personal tutor for the Masters of Clinical Research Programme.

• Articles

  • Almulhem M, Harnett N, Graham S, Haq I, Visram S, Ward C, Brodlie M. . BMJ Open Respiratory Research 2022, 9, e001420.
  • Jackson RM, Hatton CF, Spegarova JS, Georgiou M, Collin J, Stephenson E, Verdon B, Haq IJ, Hussain R, Coxhead JM, Mudhar H-S, Wagner B, Hasoon M, Davey T, Rooney P, Khan A, Ward C, Brodlie M, Haniffa M, Hambleton S, Armstrong L, Figueiredo F, Queen R, Duncan CJ, Lako M. . Stem Cell Reports 2022, 17(7), 1699-1713.
  • Zainal Abidin N, Gardner AI, Robinson H, Haq IJ, Thomas MF, Brodlie M. . Journal of Cystic Fibrosis 2021, 20(5), 737-741.
  • Gardner AI, Wu Y, Verhaegh R, Liu Y, Wilker B, Soddemann M, Keitsch S, Edwards MJ, Haq IJ, Kamler M, Becker KA, Brodlie M, Gulbins E. . Journal of Biological Chemistry 2021, 296, 100650.
  • Hatton CF, Botting RA, Duenas ME, Haq IJ, Verdon B, Thompson BJ, Spegarova JS, Gothe F, Stephenson E, Gardner AI, Murphy S, Scott J, Garnett JP, Carrie S, Powell J, Khan CMA, Huang L, Hussain R, Coxhead J, Davey T, Simpson AJ, Haniffa M, Hambleton S, Brodlie M, Ward C, Trost M, Reynolds G, Duncan CJA. . Nature Communications 2021, 12(1), 7092.
  • Shteinberg M, Haq IJ, Polineni D, Davies JC. . The Lancet 2021, 397(10290), 2195-2211.
  • Bain R, Cosgriff R, Zampoli M, Elbert A, Burgel P-R, Carr SB, Castaños C, Colombo C, Corvol H, Faro A, Goss CH, Gutierrez H, Jung A, Kashirskaya N, Marshall BC, Melo J, Mondejar-Lopez P, de Monestrol I, Naehrlich L, Padoan R, Pastor-Vivero MD, Rizvi S, Salvatore M, Ferreira da Silva Filho LVR, Brownlee KG, Haq IJ, Brodlie M. . Journal of Cystic Fibrosis 2021, 20(1), 25-30.
  • Haq IJ, Althaus M, Gardner AI, Yeoh HY, Joshi U, Saint-Criq V, Verdon B, Townshend J, O'Brien C, Ben-Hamida M, Thomas M, Bourke S, van der Sluijs P, Braakman I, Ward C, Gray MA, Brodlie M. . American Journal of Physiology Lung Cellular and Molecular Physiology 2021, 320(2), L288-L300.
  • Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, Ward C, Schuchman EH, Gulbins E, Brodlie M. . American Journal of Respiratory and Critical Care Medicine 2020, 202(8), 1133-1145.
  • Saint-Criq V, Haq IJ, Gardner AI, Garnett JP, Ward C, Brodlie M, Gray MA. . Journal of Visualized Experiements 2019, (148), e59815.
  • Haq IJ, Battersby AC, Eastham K, McKean M. . BMJ 2017, 356, j686.
  • Ibrahim SH, Turner MJ, Saint-Criq V, Garnett J, Haq IJ, Brodlie M, Ward C, Borgo C, Salvi M, Venerando A, Gray MA. . Pflügers Archiv - European Journal of Physiology 2017, 469(9), 1073-1091.
  • Zainal Abidin N, Haq IJ, Gardner AI, Brodlie M. . Expert Opinion on Pharmacotherapy 2017, 18(13), 1363-1371.
  • Haq IJ, Gray MA, Garnett JP, Ward C, Brodlie M. . Thorax 2016, 71(3), 284-287.
  • Brodlie M, Haq IJ, Roberts K, Elborn JS. . Genome Medicine 2015, 7(1), 101.
  • Haq I, Gopalakaje S, Fenton AC, McKean MC, O'Brien C, Brodlie M. . Paediatric Respiratory Reviews 2014, 15(2), 124-134.
  • Haq IJ, Steinberg LJ, Hoenig M, van der Burg M, Villa A, Cant AJ, Middleton PG, Gennery AR. . Clinical Immunology 2007, 124(2), 165-169.

• Book Chapter

  • Abidin NZ, Naples R, Powell S, Gabra H, De Rita F, McDonald L, Thomas MF, O'Brien CJ, Haq IJ, Tinnion R, Brodlie M. . In: Sinha IP; Bhatt JM; Cleator A; Wallace H, ed. Respiratory Diseases of the Newborn Infant. Sheffield: European Respiratory Society, 2021, pp.147-163.

• Editorials

  • Haq I, Harris C, Taylor J, McKean MC, Brodlie M. . Archives of Disease in Childhood 2017, 102(11), 997-998.
  • Haq IJ, Gardner A, Brodlie M. . Annals of Translational Medicine 2016, 4(1), 12.

• Reviews

  • Almulhem M, Ward C, Haq I, Gray RD, Brodlie M. . BMJ Open Respiratory Research 2024, 11(1), e002456.
  • Haq I, Almulhem M, Soars S, Poulton D, Brodlie M. . Pharmacogenomics and Personalized Medicine 2022, 15, 91-104.
  • Haq IJ, Parameswaran MC, Abidin NZ, Socas A, Gonzalez-Ciscar A, Gardner AI, Brodlie M. . Paediatrics and Child Health 2019, 29(4), 151-157.