麻豆传媒

Background:

PhD Paediatric Oncology, 麻豆传媒

BSc (Hons) Biomedical Sciences, 麻豆传媒

Undergraduate Teaching:

• BGM1002 Biochemistry (Module Leader)
• CMB1004 Cell Biology
• PED1003 Pharmacology
• CMB1011 Professional and Practical Skills for Bioscientists (Semesters 1 and 2)
• BMS2023 The Principles of Cancer (Module Leader)
• PSC2002 Membrane Transport and Cell Signalling in Health and Disease
• PED2001 Drug Disposition and Pharmacokinetics
• CMB3000 Research Project
• BMS3010 Genetics and Human Disease
• BMS3012 Cancer Biology and Therapy
• BGM3024 The Molecular Basis of Cancer
• BGM3065 Biochemistry of Cancer and Chronic Diseases

Current Roles and Responsibilities:

Chair Stage 1 BoE

Academic Secretary BoE

Stage 2 Co-Lead

Personal Tutor

BMS CC

Pharmacology CC

Academic Lead for Study Skills

Previous Roles and Responsibilities:

Phase 1 Advisor

Academic Practice Advisor

UCAS for Medicine and Dentistry

Research Supervision:

Undergraduate, MRes, MPhil and PhD students. 

Summer placement students.

Research Interests:

My main research interest is in the area of paediatric cancer. Specifically, I am interested in the identification of novel targeted therapies and combination therapies for the treatment of neuroblastoma, as well as the development and use of preclinical models of neuroblastoma. Through my research I have developed successful collaborations with international academic research groups and Pharma.

Funding:

• CCLG & the Little Princess Trust
• Neuroblastoma UK & Niamh’s Next Step
• SPARKs & the Dubois Child Cancer Fund
• 麻豆传媒 Healthcare Charity
• FMS travel grant
• NECCRF travel grant
• SPARKs travel grant
• NICR travel grant

• Articles

  • Tucker ER, Jimenez I, Chen L, Bellini A, Gorrini C, Calton E, Gao Q, Che H, Poon E, Jamin Y, Martins Da Costa B, Barker K, Shrestha S, Hutchinson JC, Dhariwal S, Goodman A, Del Nery E, Gestraud P, Bhalshankar J, Iddir Y, Saberi-Ansari E, Saint-Charles A, Geoerger B, Marques Da Costa ME, Pierre-Eugene C, Janoueix-Lerosey I, Decaudin D, Nemati F, Carcaboso AM, Surdez D, Delattre O, George SL, Chesler L, Tweddle DA, Schleiermacher G. . Clinical Cancer Research 2023, 29(7), 1317-1331.
  • King D, Southgate HED, Roetschke S, Gravells P, Fields L, Watson JB, Chen L, Chapman D, Harrison D, Yeomanson D, Curtin NJ, Tweddle DA, Bryant HE. . Cancers 2021, 13(24), 6215.
  • Merugu S, Chen L, Gavens E, Gabra H, Brougham M, Makin G, Ng A, Murphy D, Gabriel AS, Robinson ML, Wright JH, Burchill SA, Humphreys A, Bown N, Jamieson D, Tweddle DA. . Clinical Cancer Research 2020, 26(1), 122-134.
  • Southgate HED, Chen L, Tweddle DA, Curtin NJ. . Cancers 2020, 12(5), 1095.
  • Chen L, Pastorino F, Berry P, Bonner J, Kirk C, Wood KM, Thomas HD, Zhao Y, Daga A, Veal GJ, Lunec J, Newell DR, Ponzoni M, Tweddle DA. . International Journal of Cancer 2019, 144(12), 3146-3159.
  • Chen L, Esfandiari A, Reaves W, Vu A, Hogarty MD, Lunec J, Tweddle DA. . International Journal of Oncology 2018, 52(3), 967-977.
  • Chen L, Humphreys A, Turnbull L, Bellini A, Schleiermacher G, Salwen H, Cohn SL, Bown N, Tweddle DA. . Oncotarget 2016, 7, 87301-87311.
  • Evans L, Chen L, Milazzo G, Gherardi S, Perini G, Willmore E, Newell DR, Tweddle DA. . Cancer Letters 2015, 363(1), 37-45.
  • Chen L, Rousseau RF, Middleton SA, Nichols GL, Newell DR, Lunec J, Tweddle DA. . Oncotarget 2015, 6(12), 10207-10221.
  • Chen L, Tweddle DA. . Pediatric and Adolescent Medicine 2015, 20, 59-80.
  • Chen L, Zhao Y, Halliday GC, Berry P, Rousseau RF, Middleton SA, Nichols GL, Del Bello F, Piergentili A, Newell DR, Lunec J, Tweddle DA. . British Journal of Cancer 2014, 111, 716-725.
  • Bell E, Chen L, Viprey VF, Blanchard GB. . Pediatric Blood & Cancer 2014, 61(9), 1711-1713.
  • Chen L, Tweddle DA. . Frontiers in Oncology 2012, 2, 173.
  • Chen L, Iraci N, Gherardi S, Gamble LD, Wood KM, Perini G, Lunec J, Tweddle DA. . Cancer Research 2010, 70(4), 1377-1388.
  • Chen L, Malcolm AJ, Wood K, Cole M, Variend S, Cullinane C, Pearson ADJ, Lunec J, Tweddle DA. . Cell Cycle 2007, 6(21), 2685-2696.

• Book Chapter

  • Chen L, Tweddle DA. . In: Christiansen, H and Christiansen, NM, ed. Progressive Neuroblastoma: Innovation and Novel Therapeutic Strategies. Karger, 2015, pp.59-80.

• Conference Proceedings (inc. Abstracts)

  • Chen L, Pastorino F, Berry P, Bonner J, Wood K, Veal G, Ponzoni M, Lunec J, Newell DR, Tweddle DA. . In: AACR Annual Meeting 2017. 2017, Washington, DC: American Association for Cancer Research.
  • Wright JH, Humphreys A, Gabriel AS, Bown N, Chen L, Jamieson D, Tweddle DA. . In: 48th Annual Congress of the International Society of Paediatric Oncology (SIOP). 2016, Dublin, Ireland: Wiley Periodicals, Inc.
  • Gabriel AS, Chen L, Evans L, Nakjang S, Bown N, Williamson D, Tweddle DA. . In: NCRI 2016. 2016, Liverpool, UK.

• Reviews

  • Southgate HED, Chen L, Curtin NJ, Tweddle DA. . Frontiers in Oncology 2020, 10, 371.
  • Bell E, Chen LD, Liu T, Marshall GM, Lunec J, Tweddle DA. . Cancer Letters 2010, 293(2), 144-157.