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Staff Profile

Dr David Jamieson

Senior Research Associate

  • Address: University of Â鶹´«Ã½ upon Tyne
    Translational and Clinical Research Institute.
    Paul O'Gorman Building
    Medical School
    Framlington Place
    Â鶹´«Ã½ upon Tyne
    NE2 4HH
Background
Qualifications
  • BSc (Hons), Biomedical Sciences, Northumbria University.
  • PhD, Â鶹´«Ã½.

 

Administrative responsibilities
  • Member of the executive board of Northern Institute for Cancer Research
  • RA representative to senior staff meetings.
  • Lab tissue culture co-ordinator
  • Establishing and running Imagestream/CTC research group.

 

Membership
  • British Association of Cancer Research
Research
Research interests
  • Investigation, development and validation of biomarkers for pharmacodynamic endpoints in early phase clinical trials.
  • Establishment of methods to detect circulating tumour cells.
  • Imaging flow cytometry and quantitative image analysis.
  • Pharmacogenetics.

 

Grants received


  • Lead by J. Llovet on behalf of the THRIVE consortium. Tumour-host interactions in liver cancer of childhood and adults. EU Horizon MISS 2023. Autumn 2023 to autumn 2028. €11,995,060.5 awarded (of which €1,380,141.25 allocated to Â鶹´«Ã½ & €218,216.25 allocated to The Â鶹´«Ã½ upon Tyne Hospitals NHS Foundation Trust)
  • H. Reeves, D Jamieson R, Shukla. Identification of ‘liquid biopsy’ predictive biomarkers in patients with advanced hepatocellular carcinoma. The Alice Stephenson Bequest PhD studentship. September 2022 to September 2025.
  • H. Reeves, D Palmer, S Wedge, D Jamieson R, Shukla. Liver Cancer – Developing DNA-PK as a predictive biomarker and clinical target. MRC DiMeN DTP studentships. September 2021 to September 2024.
  • D Jamieson. CTC, IHC and Nanostring pharmacodynamic assays for MIV-818 phase I trial. Medivir. August 2018 to July 2021. £269,572 awarded.
  • D Jamieson. AZD3965 - A monocarboxylate transporter 1 inhibitor in patients with advanced cancer. CRUK. February 2018 to February 2020. £16,424 awarded
  • AP Greystoke, D Jamieson, GJ Veal. PD Biomarkers Centre of Excellence. CDD. May 2017 to May 2019. £137,600 awarded
  • DA Tweddle, L Chen, D Jamieson. Understanding neuroblastoma heterogeneity: Genetic studies of circulating neuroblastoma tumour cells. CCLG December 2016 to November 2017. £37,875.14 awarded.
  • AP Greystoke, D Jamieson, GJ Veal, SR Wedge. MOv18 Phase I Study. CRUK. October 2015 to October 2018. £13,860.00 awarded. 
  • AP Greystoke, D Jamieson, GJ Veal. LY314921 SUA PD Biomarker. CRUK. July 2016 to July 2017. £29,077.31 awarded.
  • AP Greystoke, D Jamieson, GJ Veal. A pilot project to investigate the added utility of circulating miRNAs in distinguishing between response and toxicity in patients with primary brain tumours treated with chemoradiotherapy. JGWP. September 2016 to July 2018. £41,139.11 awarded.
  • D Jamieson. CTC pharmacodynamic assay for C/EBPa saRNA phase I trial. MINA Alpha Limited. July 2016 to March 2019. £46,368 awarded.
  • GJ Veal, Jamieson D. Pharmacogenetics of Doxorubicin, Gemcitabine and Docetaxel in Patients studied on the GeDDiS trial (Sarcoma). Sarcoma UK. August 2015 to August 2016. £22,317.16 awarded.
  • UK Mallick, V Paleri, GJ Veal, P Perros, TWJ Lennard, ER Plummer, D Jamieson. Feasibility of detection and enumeration of Circulating Tumour Cells in Thyroid Cancer using the Veridex LLC (Cell-Search) and the ImageStreamX Mark II (Amnis) flow cytometry methods – A Â鶹´«Ã½-Manchester joint pilot study. Â鶹´«Ã½ Healthcare Charity. December 2014 to December 2015. £30,479.80 awarded.
  • Boddy AV, Jamieson D, Dean J. Welcome Trust Biomedical Vacation Scholarship. June to July 2013. £1,440 awarded.
  • FEB May, D Jamieson, SM Griffin. Prognostic, predictive and pharmacodynamic value of circulating tumour cells in oesophagogastric cancer patients in receipt of palliative systemic therapy. JGWP. November 2013 to December 2015. £46,136 awarded.
  • D Jamieson, AV Boddy, R Plummer, N Curtain, H Reeves, R Edmondson, C Robson, FEB May: Development of CTC assays. NICR Pump Priming funds. April 2012 to April 2013. £90,000 awarded.
  • D Jamieson, AV Boddy, R Plummer: Capital costs for purchase of ImageStreamX imaging flow cytometer. Bobby Robson Foundation. 2012, £420,000 awarded.
  • D Jamieson, FEB May, AV Boddy: Application to JGWP for consumable money to investigate NQO2 in kinase mediated signalling in breast cancer – 2008 to 2009, £16, 561 awarded.
  • AV Boddy, D Jamieson, KKN Chan: Relationship between genotype and reductase enzyme activity in bladder and ovarian tumours. Nuffield Science Bursaries Undergraduate Research. July 2007-August 2007. £1,360 awarded.
  • D Jamieson & HY Leung: Establishment of a high throughput screen for modifiers of apoptosis and cell cycle kinetics in a metastatic prostate cancer cell line for drug and drug target discovery. Â鶹´«Ã½ NHS Special Trustees, project grant. July 2006-June 2007. £47,000 awarded.


Teaching
Teaching responsibilities
  • Undergraduate lecture on the use of alkylating agents in cancer chemotherapy.
  • Joint module leader on Oncology and Palliative Care MSc: Pharmacology of Anticancer Drugs
  • Supervision of undergraduates, masters and PhD students.
Publications

  • Articles

    • Danilenko M, Nath S, Baines J, Gordon F, Merugu S, Allinson LM, Potts A, Collins B, Goodman A, Kidman SE, McAnulty C, Jamieson D, Tweddle DA. . International Journal of Molecular Sciences 2025, 26(19), 9466.
    • Gulati P, Carruthers V, Hutton C, Cassidy C, Amankwatia EB, Pascual S, Florence E, Gebru TG, Jorgensen AL, Greystoke A, Makin G, McCabe MG, Hawcutt DB, Veal GJ, Jamieson D. . EJC Paediatric Oncology 2025, 5, 100216.
    • Barnett S, Nyein AC, Galler M, Jamieson D, Davies M, Connor P, Veal GJ. . Cancer Chemotherapy and Pharmacology 2023, 92, 325–328.
    • Idowu OS, Craigen JL, Veal GJ, Jamieson D. . Bioanalysis 2022, 14(18), 1241-1249.
    • Barnett S, Errington J, Sludden J, Jamieson D, Poinsignon V, Paci A, Veal GJ. . Pharmaceuticals 2021, 14(3), 272.
    • Doan M, Case M, Masic D, Hennig H, McQuin C, Caicedo J, Singh S, Goodman A, Wolkenhauer O, Summers H, Jamieson D, van Delft FW, Filby A, Carpenter A, Rees P, Irving J. . Cytometry A 2020, 97(4), 407-414.
    • Hellmann F, Völler S, Krischke M, Jamieson D, André N, Bisogno G, Boddy A, Hempel G. Genetic Polymorphisms Affecting Cardiac Biomarker Concentrations in Children with Cancer: an Analysis from the “European Paediatric Oncology Off-patents Medicines Consortium” (EPOC) Trial. European Journal of Drug Metabolism and Pharmacokinetics 2020. In Preparation.
    • Merugu S, Chen L, Gavens E, Gabra H, Brougham M, Makin G, Ng A, Murphy D, Gabriel AS, Robinson ML, Wright JH, Burchill SA, Humphreys A, Bown N, Jamieson D, Tweddle DA. . Clinical Cancer Research 2020, 26(1), 122-134.
    • Uitrakul S, Hutton C, Veal GJ, Jamieson D. . European Journal of Clinical Investigation 2019, 49(7), e13115.
    • Margetts J, Ogle LF, Chan SL, Chan AWH, Chan KCA, Jamieson D, Willoughby CE, Mann DA, Wilson CL, Manas DM, Yeo W, Reeves HL. . British Journal of Cancer 2018, 118, 248-257.
    • Fordham SE, Blair HJ, Elstob CJ, Plummer R, Drew Y, Curtin NJ, Heidenreich O, Pal D, Jamieson D, Park C, Pollard J, Fields S, Milne P, Jackson GH, Marr HJ, Menne T, Jones GJ, Allan JM. . Blood Advances 2018, 2(10), 1157-1169.
    • Ribeiro R, Pal D, Jamieson D, Rankin K, Benning M, Dalgarno K, Ferreira A. . ACS Applied Materials & Interfaces 2017, 9(15), 12967-12974.
    • Jamieson D, Sunter N, Muro S, Pouché L, Cresti N, Lee J, Sludden J, Griffin MJ, Allan JM, Verrill MW, Boddy AV. . European Journal of Cancer 2017, 71, 15-24.
    • Seddon B, Strauss SJ, Whelan J, Leahy M, Woll PJ, Cowie F, Rothermundt C, Wood Z, Benson C, Ali N, Marple M, Veal G, Jamieson D, Küver K, Tirabosco R, Forsyth S, Nash S, Dehbi H, Beare S. . Lancet Oncology 2017, 18(10), 1397-1410.
    • Drew Y, Ledermann J, Hall G, Rea D, Glasspool R, Highley M, Jayson G, Sludden J, Murray J, Jamieson D, Halford S, Acton G, Backholer Z, Mangano R, Boddy A, Curtin N, Plummer R. . British Journal of Cancer 2016, 114(7), 723-730.
    • Ogle LF, Orr JG, Willoughby CE, Hutton C, McPherson S, Plummer R, Boddy AV, Curtin NC, Jamieson D, Reeves HL. . Journal of Hepatology 2016, 65(2), 305-313.
    • Dent BM, Ogle LF, O'Donnell RL, Hayes N, Mallick U, Curtin NJ, Boddy AV, Plummer ER, Edmondson RJ, Reeves HL, May FEB, Jamieson D. . International Journal of Cancer 2016, 138(1), 206-216.
    • Cresti N, Lee J, Rourke E, Televantou D, Jamieson D, Verrill M, Boddy AV. . European Journal of Cancer 2016, 55, 27-37.
    • Veal GJ, Cole M, Chinnaswamy G, Sludden J, Jamieson D, Errington J, Malik G, Hill CR, Chamberlain T, Boddy AV. . European Journal of Cancer 2016, 55, 56–64.
    • Woodward J, Taylor GC, Soares DC, Boyle S, Sie D, Read D, Chathoth K, Vukovic M, Tarrats N, Jamieson D, Campbell KJ, Blyth K, Acosta JC, Ylstra B, Arends MJ, Kranc KR, Jackson AP, Bickmore WA, Wood AJ. . Genes & Development 2016, 30, 2173-2186.
    • Jamieson D, Griffin MJ, Sludden J, Drew Y, Cresti N, Swales K, Merriman M, Allen R, Bevan P, Buerkle M, Mala C, Coyle V, Rodgers L, Dean E, Greystoke A, Banerji U, Wilson RH, Evans TRJ, Anthoney A, Ranson M, Boddy AV, Plummer R. . European Journal of Cancer 2016, 68, 1-10.
    • Jamieson D, Lee J, Cresti N, Jackson R, Griffin M, Sludden J, Verrill M, Boddy AV. . Cancer Chemotherapy and Pharmacology 2014, 74(4), 667-674.
    • Mould E, Berry P, Jamieson D, Hill C, Cano C, Tan N, Elliott S, Durkacz B, Newell D, Willmore E. . Biochemical Pharmacology 2014, 88(1), 58-65.
    • Hill CR, Jamieson D, Thomas HD, Brown CDA, Boddy AV, Veal GJ. . Biochemical Pharmacology 2013, 85(1), 29-37.
    • Armstrong JL, Martin S, Illingworth NA, Jamieson D, Neilson A, Lovat PE, Redfern CPF, Veal GJ. . Oncology Reports 2012, 27(1), 293-298.
    • Daly AK, Veal GJ, Jamieson D, Coulthard S. . Pharmacogenomics 2012, 13(12), 1333-1338.
    • Jamieson D, Cresti N, Bray J, Sludden J, Griffin MJ, Hawsawi NM, Famie E, Mould EVA, Verrill MW, May FEB, Boddy AV. . Pharmacogenetics and Genomics 2011, 21(12), 808-819.
    • Weatherhead SC, Farr PM, Jamieson D, Hallinan JS, Lloyd JL, Wipat A, Reynolds NJ. . Journal of Investigative Dermatology 2011, 131(9), 1916-1926.
    • Bray J, Sludden J, Griffin MJ, Cole M, Verrill M, Jamieson D, Boddy AV. . British Journal of Cancer 2010, 102(6), 1003-1009.
    • Jamieson D, Cresti N, Verrill MW, Boddy AV. . Journal of Immunological Methods 2009, 345(1-2), 106-111.
    • Jamieson D, Wilson K, Pridgeon S, Margetts J, Edmondson R, Leung H, Knox R, Boddy AV. . Clinical Cancer Research 2007, 13(5), 1584-1590.
    • Jamieson, D., Tung, A., Knox, R., Boddy, A. . British Journal of Cancer 2006, 95(9), 1229-1233.

  • Book Chapter

    • Jamieson D. . In: Schwab, M, ed. Encyclopedia of Cancer. Berlin: Springer-Verlag, 2008.

  • Conference Proceedings (inc. Abstracts)

    • Macheka S, Jamieson D, Reeves H, McCain M. . In: 6th Christie International Student Cancer Conference. 2016, Manchester: International Institute of Anticancer Research.
    • Greystoke A, Hogarth L, Patterson M, Williams I, Ness T, Georgiadis K, Bolt L, Bettison I, Turner D, Jamieson D, Simmons T, Hughes A, Jaedicke K, Gardiner J, Mulvenna P, Leaning D, Bradshaw A, Butler R, Black F. . In: 14th Annual British Thoracic Oncology Group Conference 2016. 2016, Dublin, Ireland: Elsevier.
    • Wright JH, Humphreys A, Gabriel AS, Bown N, Chen L, Jamieson D, Tweddle DA. . In: 48th Annual Congress of the International Society of Paediatric Oncology (SIOP). 2016, Dublin, Ireland: Wiley Periodicals, Inc.
    • Wyatt N, Hogarth L, Turner D, Patterson M, Jamieson D, Black F, Hutton C, Mulvenna P, Simmons T, Bradshaw A, Kolenda C, Parker C, Martin-Ruiz C, Greystoke A. . In: IASLC 17th World Conference on Lung Cancer. 2016, Vienna, Austria: Elsevier.
    • Ogle L, Jamieson D, O'Donnell R, Dent B, Boddy A, Curtin N, Plummer R, Reeves H, Clinical and Translational Group. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
    • Dent B, O'Donnell RL, Ogle LF, Rourke ED, Ramesh HP, Moat M, Hayes N, Mallick UK, May FE, Reeves HL, Curtain NJ, Edmondson RJ, Boddy AV, Plummer R, Jamieson D. . In: AACR Annual Meeting 2014. 2014, San Diego, CA: American Association for Cancer Research.
    • Mould E, Berry P, Jamieson D, Hill C, Tan N, Elliott S, Durkacz B, Newell D, Willmore E. . In: American Association for Cancer Research 104th Annual Meeting. 2013, Washington, DC, USA: American Association for Cancer Research.
    • Moat M, ODonnell R, Dent B, Ogle L, Curtin NJ, Jamieson D, Edmondson RJ. . In: 18th International Meeting of the European Society of Gynaecological Oncology (ESGO). 2013, Liverpool, UK: Lippincott Williams & Wilkins.
    • Boddy AV, Cresti N, Jamieson D, Pinkilgton M, Verrill MW. Single nucleotide polymorphisms and expression/amplification of HER2 in patients with breast cancer. In: JOURNAL OF CLINICAL ONCOLOGY. 2011, 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA: AMER SOC CLINICAL ONCOLOGY.
    • Cresti N, Jamieson D, Verrill MW, Pinkilgton M, Boddy AV. Fc gamma-receptor IIa polymorphism and cardiotoxicity in patients with breast cancer treated with adjuvant trastuzumab. In: JOURNAL OF CLINICAL ONCOLOGY. 2011, 2318 MILL ROAD, STE 800, ALEXANDRIA, VA 22314 USA: AMER SOC CLINICAL ONCOLOGY.
    • Weatherhead S, Farr P, Swan D, Jamieson D, Hallinan J, Lloyd J, Wipat A, Reynolds N. . In: 41st Annual Meeting of the European Society for Dermatological Research. 2011, Barcelona, Spain: Nature Publishing Group.
    • Weatherhead SC, Jamieson D, Reynolds NJ. . In: British Journal of Dermatology: Annual Meeting of the British Society for Investigative Dermatology. 2009, Royal Agricultural College, Cirencester, UK: Wiley-Blackwell.
    • Weatherhead SC, Jamieson D, Reynolds NJ. . In: Journal of Investigative Dermatology: 39th Annual Meeting of the European Society for Dermatological Research (ESDR). 2009, Budapest, Hungary: Nature Publishing Group.

  • Reviews

    • Jamieson D, Boddy AV. . Expert Opinion on Drug Metabolism and Toxicology 2011, 7(10), 1201-1210.
    • Cresti N, Jamieson D. . Clinical Medicine Reviews in Oncology 2010, 2, 149-165.