麻豆传媒

Background

Mitochondrial diseases are common genetic disorders caused by defective energy production. They affect numerous organs and due to the clinical and genetic heterogeneity, obtaining a genetic diagnosis is often difficult yet crucial for the counselling of patients and their families. There are no cures but establishing a genetic diagnosis enables patients and their families’ access to genetic and reproductive counselling.

I am a State Registered Clinical Scientist and have spent the last 17 years working in the Nationally-Commissioned mitochondrial diagnostic laboratory in 麻豆传媒. Our current testing strategy relies upon functional analysis of a muscle biopsy and selective candidate gene sequencing; whilst this strategy establishes a genetic diagnosis for many patients, approximately half our patients remain without a genetic diagnosis. 

I am particularly interested in paediatric mitochondrial disease, and spent much of my PhD improving the genetic diagnosis pathway for paediatric patients with mitochondrial disease through implementation of next-generation sequencing (NGS) technologies within a diagnostic setting.

For families who have lost a child, establishing a genetic diagnosis means that we can offer reproductive options to Mum and Dad such as prenatal testing by either chorionic villus biopsy or amniocentesis enables us to determine - from as early as 10 weeks of gestation - whether their subsequent pregnancies have inherited the same gene mutations.

My doctoral work has been remarkably successful in obtaining a rapid genetic diagnosis for patients and their families, and has enabled us to undertake prenatal testing for a number of families. 

A targeted approach to genetic diagnosis of paediatric complex I deficiency has shown that many patients' genetic defects affect a gene outwith those that encode the structural subunits and assembly factors of complex I, revealing that isolated complex I deficiency is considerably more genetically heterogeneous than initially suspected. We remain optimistic that we will be able to obtain a genetic diagnosis for these undiagnosed patients as our diagnostic algorithm continues to expand.

My recent research focuses on the diagnosis of the more challenging cases, through application of transciptomics and long read sequencing using pac bio and ONT pipelines.

Qualifications

2017                         PhD, 麻豆传媒

2003                         BSc (Hons) Genetics (Immunology), University of Aberdeen

Professional Bodies

2022-present Fellow of the Royal College of Pathologists

2007-present             HCPC registered Clinical Scientist                CS17436

Society Membership

2004-present              British Society of Genetic Medicine

Committees

2022 - present Clinical Ethics Advisory Group - 麻豆传媒 Hospitals

MMB8034 - The Diagnosis of Mitochondrial Disease - 麻豆传媒

NHS STP (Genomics) - University of Manchester

• Articles

  • Watson-Fargie T, Coomber A, Edwards R, Barr M, Brennan K, Fletcher E, Miller-Hodges E, O'Sullivan D, Stewart K, Hopton S, He L, Alston CL, Taylor RW, Topf A, Straub V, Stewart W, Longman C, Farrugia ME. . Neuromuscular Disorders 2025, 49, 105343.
  • Buhl E, Garg S, Monaghan M, Preston A, Likeman M, Dare J, Evans J, Taylor LS, Berry I, Urankar K, Spry PGD, Williams C, Taylor RW, Alston CL, Hodge JJL, Majumdar A. . Clinical Genetics 2025, 108(3), 266-278.
  • Falabella M, Pizzamiglio C, Tabara LC, Munro B, Abdel-Hamid MS, Sonmezler E, Macken WL, Lu S, Tilokani L, Flannery PJ, Patel N, Pope SAS, Heales SJR, Hammadi DBH, Alston CL, Taylor RW, Lochmuller H, Woodward CE, Labrum R, Vandrovcova J, Houlden H, Chronopoulou E, Pierre G, Maroofian R, Hanna MG, Taanman J-W, Hiz S, Oktay Y, Zaki MS, Horvath R, Prudent J, Pitceathly RDS. . Brain 2025, 148(2), 647-662.
  • Sung AY, Guerra RM, Steenberge LH, Alston CL, Murayama K, Okazaki Y, Shimura M, Prokisch H, Ghezzi D, Torraco A, Carrozzo R, Rotig A, Taylor RW, Keck JL, Pagliarini DJ. . Nature Metabolism 2024, 6, 1128–1142.
  • Correia SP, Moedas MF, Taylor LS, Naess K, Lim AZ, McFarland R, Kazior Z, Rumyantseva A, Wibom R, Engvall M, Bruhn H, Lesko N, Vegvari A, Kall L, Trost M, Alston CL, Freyer C, Taylor RW, Wedell A, Wredenberg A. . JCI Insight 2024, 9(20), e178645.
  • Mavraki E, Labrum R, Sergeant K, Alston CL, Woodward C, Smith C, Knowles CVY, Patel Y, Hodsdon P, Baines JP, Blakely EL, Polke J, Taylor RW, Fratter C. . European Journal of Human Genetics 2023, 31, 148-163.
  • Nolden KA, Egner JM, Collier JJ, Russell OM, Alston CL, Harwig MC, Widlansky ME, Sasorith S, Barbosa IA, Douglas AG, Baptista J, Walker M, Donnelly DE, Morris AA, Tan HJ, Kurian MA, Gorman K, Mordekar S, Deshpande C, Samanta R, McFarland R, Hill RB, Taylor RW, Olahova M. . Life Science Alliance 2022, 5(12), e202101284.
  • Lim AZ, Ng YS, Blain A, Jiminez-Moreno C, Alston CL, Nesbitt V, Simmons L, Santra S, Wassmer E, Blakely EL, Turnbull DM, Taylor RW, Gorman GS, McFarland R. . Annals of Neurology 2022, 91(1), 117-130.
  • Yepez VA, Gusic M, Kopajtich R, Mertes C, Smith NH, Alston CL, Ban R, Beblo S, Berutti R, Blessing H, Ciara E, Distelmaier F, Freisinger P, Haberle J, Hayflick SJ, Hempel M, Itkis YS, Kishita Y, Klopstock T, Krylova TD, Lamperti C, Lenz D, Makowski C, Mosegaard S, Muller MF, Munoz-Pujol G, Nadel A, Ohtake A, Okazaki Y, Procopio E, Schwarzmayr T, Smet J, Staufner C, Stenton SL, Strom TM, Terrile C, Tort F, Van Coster R, Vanlander A, Wagner M, Xu M, Fang F, Ghezzi D, Mayr JA, Piekutowska-Abramczuk D, Ribes A, Rotig A, Taylor RW, Wortmann SB, Murayama K, Meitinger T, Gagneur J, Prokisch H. . Genome Medicine 2022, 14(1), 38.
  • Lujan SA, Longley MJ, Humble MH, Lavender CA, Burkholder A, Blakely EL, Alston CL, Gorman GS, Turnbull DM, McFarland R, Taylor RW, Kunkel TA, Copeland WC. . Genome Biology 2020, 21(1), 248.
  • Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW. . American Journal of Human Genetics 2020, 106(1), 92-101.
  • Cotta A, Alston CL, Baptista-Junior S, Paim JF, Carvalho E, Navarro MM, Appleton M, Ng YS, Valicek J, da-Cunha-Junior AL, Lima MI, de la Rocque Ferreira A, Takata RI, Hargreaves IP, Gorman GS, McFarland R, Pierre G, Taylor RW. . JIMD Reports 2020, 54(1), 45-53.
  • Alahmad A, Nasca A, Heidler J, Thompson K, Olahova M, Legati A, Lamantea E, Meisterknecht J, Spagnolo M, He L, Alameer S, Hakami F, Almehdar A, Ardissone A, Alston CL, McFarland R, Wittig I, Ghezzi D, Taylor RW. . EMBO Molecular Medicine 2020, 12(11), e12619.
  • Ng YS, Martikainen MH, Gorman GS, Blain A, Bugiardini E, Bunting A, Schaefer AM, Alston CL, Blakely EL, Sharma S, Hughes I, Lim A, de Goede C, McEntagart M, Spinty S, Horrocks I, Roberts M, Woodward CE, Chinnery PF, Horvath R, Nesbitt V, Fratter C, Poulton J, Hanna MG, Pitceathly RDS, Taylor RW, Turnbull DM, McFarland R. . Annals of Neurology 2019, 86(2), 310-315.
  • Saoura M, Powell CA, Kopajtich R, Alahmad A, Al-Balool HH, Albash B, Alfadhel M, Alston CL, Bertini E, Bonnen PE, Bratkovic D, Carrozzo R, Donati MA, Di Nottia M, Ghezzi D, Goldstein A, Haan E, Horvath R, Hughes J, Invernizzi F, Lamantea E, Lucas B, Pinnock K-G, Pujantell M, Rahman S, Rebelo-Guiomar P, Santra S, Verrigni D, McFarland R, Prokisch H, Taylor RW, Levinger L, Minczuk M. . Human Mutation 2019, 40(10), 1731-1748.
  • Olahova M, Berti CC, Collier JJ, Alston CL, Jameson E, Jones SA, Edwards N, He L, Chinnery PF, Horvath R, Goffrini P, Taylor RW, Sayer JA. . Human Molecular Genetics 2019, 28(22), 3766-3776.
  • Grady JP, Pickett SJ, Ng YS, Alston CI, Blakely EL, Hardy SA, Feeney CL, Bright AA, Schaefer AM, Gorman GS, McNally RJ, Taylor RW, Turnbull DM, McFarland R. . EMBO Molecular Medicine 2018, 10(6), e8262.
  • Alaimo JT, Besse A, Alston CL, Pang K, Appadurai V, Samanta M, Smpokou P, Mcfarland R, Taylor RW, Bonnen PE. . Human Mutation 2018, 39(4), 537-549.
  • Fitzsimons PE, Alston CL, Bonnen PE, Hughes J, Crushell E, Geraghty MT, Tetreault M, O'Reilly P, Twomey E, Sheikh Y, Walsh R, Waterham HR, Ferdinandusse S, Wanders RJA, Taylor RW, Pitt JJ, Mayne PD. . American Journal of Medical Genetics, Part A 2018, 176(5), 1115-1127.
  • Repp BM, Mastantuono E, Alston CL, Schiff M, Haack TB, Rotig A, Ardissone A, Lombes A, Catarino CB, Diodato D, Schottmann G, Poulton J, Burlina A, Jonckheere A, Munnich A, Rolinski B, Ghezzi D, Rokicki D, Wellesley D, Martinelli D, Wenhong D, Lamantea E, Ostergaard E, Pronicka E, Pierre G, Smeets HJM, Wittig I, Scurr I, De Coo IFM, Moroni I, Smet J, Mayr JA, Dai L, De Meirleir L, Schuelke M, Zeviani M, Morscher RJ, McFarland R, Seneca S, Klopstock T, Meitinger T, Wieland T, Strom TM, Herberg U, Ahting U, Sperl W, Nassogne M-C, Ling H, Fang F, Freisinger P, Van Coster R, Strecker V, Taylor RW, Haberle J, Vockley J, Prokisch H, Wortmann S. . Orphanet Journal of Rare Diseases 2018, 13, 120.
  • Xu Z, Lo W-S, Beck DB, Schuch L, Olahova M, Kopajtich R, Chong YE, Alston CL, Seidl E, Zhai L, Lau C-F, Timchak D, LeDuc CA, Borczuk AC, Teich AF, Juusola J, Sofeso C, Muller C, Pierre G, Hilliard T, Turnpenny PD, Wagner M, Kappler M, Brasch F, Bouffard JP, Nangle LA, Yang X-L, Zhang M, Taylor RW, Prokisch H, Griese M, Chung WK, Schimmel P. . American Journal of Human Genetics 2018, 103(1), 100-114.
  • Alston CL, Heidler J, Dibley MG, Kremer LS, Taylor LS, Fratter C, French CE, Glasgow RIC, Feichtinger RG, Delon I, Pagnamenta AT, Dolling H, Lemonde H, Aiton N, Bjornstad A, Henneke L, Gartner J, Thiele H, Tauchmannova K, Quaghebeur G, Houstek J, Sperl W, Raymond FL, Prokisch H, Mayr JA, McFarland R, Poulton J, Ryan MT, Wittig I, Henneke M, Taylor RW. . American Journal of Human Genetics 2018, 103(4), 592-601.
  • Ng YS, Lax NZ, Maddison P, Alston CL, Blakely EL, Hepplewhite PD, Riordan G, Meldau S, Chinnery PF, Pierre G, Chronopoulou E, Du A, Hughes I, Morris AA, Kamakari S, Chrousos G, Rodenburg RJ, Saris CGJ, Feeney C, Hardy SA, Sakakibara T, Sudo A, Okazaki Y, Murayama K, Mundy H, Hanna MG, Ohtake A, Schaefer AM, Champion MP, Turnbull DM, Taylor RW, Pitceathly RDS, McFarland R, Gorman GS. . EBioMedicine 2018, 30, 86-93.
  • Alston CL, Rocha MC, Lax NZ, Turnbull DM, Taylor RW. . Journal of Pathology 2017, 241(2), 236-250.
  • Craven L, Alston CL, Taylor RW, Turnbull DM. . Annual Review of Genomics and Human Genetics 2017, 18, 257-275.
  • Lehmann D, Kornhuber ME, Clajus C, Alston CL, Wienke A, Deschauer M, Taylor RW, Zierz S. . Neurology Genetics 2017, 2(6), e133.
  • Glasgow RIC, Thompson K, Barbosa IA, He L, Alston CL, Deshpande C, Simpson MA, Morris AAM, Neu A, Löbel U, Hall J, Prokisch H, Haack TB, Hempel M, McFarland R, Taylor RW. . Neurogenetics 2017, 18(4), 227-235.
  • Martikainen MH, Grady JP, Ng YS, Alston CL, Gorman GS, Taylor RW, McFarland R, Turnbull DM. . European Journal of Human Genetics 2017, 25(10), 1162-1164.
  • Sallevelt SCEH, de Die-Smulders CEM, Hendrickx ATM, Hellebrekers DMEI, de Coo IFM, Alston CL, Knowles C, Taylor RW, McFarland R, Smeets HJM. . Journal of Medical Genetics 2017, 54(2), 114-124.
  • Sommerville EW, Alston CL, Pyle A, He L, Falkous G, Naismith K, Chinnery PF, McFarland R, Taylor RW. . Neurology Genetics 2017, 3(5), e187.
  • Sommerville EW, Ng YS, Alston CL, Dallabona C, Gilberti M, He L, Knowles C, Chin SL, Schaefer AM, Falkous G, Murdoch D, Longman C, De Visser M, Bindoff LA, Rawles JM, Dean JCS, Petty RK, Farrugia ME, Haack TB, Prokisch H, McFarland R, Turnbull DM, Donnini C, Taylor RW, Gorman GS. . JAMA Neurology 2017, 74(6), 686-694.
  • Feichtinger RG, Olahova M, Kishita Y, Garone C, Kremer LS, Yagi M, Uchiumi T, Jourdain AA, Thompson K, D'Souza AR, Kopajtich R, Alston CL, Koch J, Sperl W, Mastantuono E, Strom TM, Wortmann SB, Meitinger T, Pierre G, Chinnery PF, Chrzanowska-Lightowlers ZM, Lightowlers RN, DiMauro S, Calvo SE, Mootha VK, Moggio M, Sciacco M, Comi GP, Ronchi D, Murayama K, Ohtake A, Rebelo-Guiomar P, Kohda M, Kang D, Mayr JA, Taylor RW, Okazaki Y, Minczuk M, Prokisch H. . American Journal of Human Genetics 2017, 101(4), 525-538.
  • de Laat P, Janssen MCH, Alston CL, Taylor RW, Rodenburg RJT, Smeitink JAM. . BBA Clinical 2016, 6, 19-24.
  • Ng YS, Alston CL, Diodato D, Morris AA, Ulrick N, Kmoch S, Houstek J, Martinelli D, Haghighi A, Atiq M, Gamero MA, Garcia-Martinez E, Kratochvilova H, Santra S, Brown RM, Brown GK, Ragge N, Monavari A, Pysden K, Ravn K, Casey JP, Khan A, Chakrapani A, Vassallo G, Simons C, McKeever K, O'Sullivan S, Childs AM, Ostergaard E, Vanderver A, Goldstein A, Vogt J, Taylor RW, McFarland R. . Journal of Medical Genetics 2016, 53(11), 768-775.
  • Kennedy H, Haack TB, Hartill V, Matakovic L, Baumgartner ER, Potter H, Mackay R, Alston CL, O'Sullivan S, McFarland R, Connolly G, Gannon C, King R, Mead S, Crozier I, Chan W, Florkowski CM, Sage M, Hofken T, Alhaddad B, Kremer LS, Kopajtich R, Feichtinger RG, Sperl W, Rodenburg RJ, Minet JC, Dobbie A, Strom TM, Meitinger T, George PM, Johnson CA, Taylor RW, Prokisch H, Doudney K, Mayr JA. . American Journal of Human Genetics 2016, 99(3), 674-682.
  • Ng YS, Grady JP, Lax NZ, Bourke JP, Alston CL, Hardy SA, Falkous G, Schaefer AG, Radunovic A, Mohiddin SA, Ralph M, Alhakim A, Taylor RW, McFarland R, Turnbull DM, Gorman GS. . European Heart Journal 2016, 37(32), 2552-2559.
  • Thompson K, Majd H, Dallabona C, Reinson K, King MS, Alston CL, He LP, Lodi T, Jones SA, Fattal-Valevski A, Fraenkel ND, Saada A, Haham A, Isohanni P, Vara R, Barbosa IA, Simpson MA, Deshpande C, Puusepp S, Bonnen PE, Rodenburg RJ, Suomalainen A, Õunap K, Elpeleg O, Ferrero I, McFarland R, Kunji ERS, Taylor RW. . American Journal of Human Genetics 2016, 99(4), 860-876.
  • Metodiev MD, Thompson K, Alston CL, Morris AAM, He LP, Assouline Z, Rio M, Bahi-Buisson N, Pyle A, Griffin H, Siira S, Filipovska A, Munnich A, Chinnery PF, McFarland R, Rotig A, Taylor RW. . American Journal of Human Genetics 2016, 98(5), 993-1000.
  • Ng YS, Feeney C, Schaefer AM, Holmes CE, Hynd P, Alston CL, Grady JP, Roberts M, Maguire M, Bright A, Taylor RW, Yiannakou Y, McFarland R, Turnbull DM, Gorman GS. . Annals of Neurology 2016, 80(5), 686-692.
  • Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia CW, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JJP, Coon JJ, Pagliarini DJ. . Molecular Cell 2016, 63(4), 621-632.
  • Vincent AE, Grady JP, Rocha MC, Alston CL, Rygiel KA, Barresi R, Taylor RW, Turnbull DM. . Neuromuscular Disorders 2016, 26(10), 691-701.
  • Wilson IJ, Carling PJ, Alston CL, Floros VI, Pyle A, Hudson G, Sallevelt SCEH, Lamperti C, Carelli V, Bindoff LA, Samuels DC, Wonnapinij P, Zeviani M, Taylor RW, Smeets HJM, Horvath R, Chinnery PF. . Human Molecular Genetics 2016, 25(5), 1031-1041.
  • Vincent AE, Rosa HS, Alston CL, Grady JP, Rygiel KA, Rocha MC, Barresi R, Taylor RW, Turnbull DM. . Neuromuscular Disorders 2016, 26(11), 782-788.
  • Silwal A, Morris A, Warren D, Vadlamani G, Alston CL, Taylor RW. . Journal of Pediatric Neurology 2016, 14(3), 126-132.
  • Martikainen MH, Ng YS, Gorman GS, Alston CL, Blakely EL, Schaefer AM, Chinnery PF, Burn DJ, Taylor RW, McFarland R, Turnbull DM. . JAMA Neurology 2016, 73(6), 668-674.
  • Alston CL, Compton AG, Formosa LE, Strecker V, Oláhová M, Haack TB, Smet J, Stouffs K, Diakumis P, Ciara E, Cassiman D, Romain N, Yarham JW, He L, De Paepe B, Vanlander AV, Seneca S, Feichtinger RG, Płoski R, Rokicki D, Pronicka E, Haller RG, Van Hove JL, Bahlo M, Mayr JA, Vancoster R, Prokisch H, Wittig I, Ryan MT, Thorburn DR, Taylor RW. . American Journal of Human Genetics 2016, 99(1), 217-227.
  • Alston CL, Howard C, Oláhová M, Hardy SA, He L, Murray PG, O'Sullivan S, Doherty G, Shield JP, Hargreaves IP, Monavari AA, Knerr I, McCarthy P, Morris AA, Thorburn DR, Prokisch H, Clayton PE, McFarland R, Hughes J, Crushell E, Taylor RW. . Journal of Medical Genetics 2016, 53(9), 634-641.
  • Ferrer-Cortès X, Narbona J, Bujan N, Matalonga L, Del Toro M, Arranz JA, Riudor E, Garcia-Cazorla A, Jou C, O'Callaghan M, Pineda M, Montero R, Arias A, Garcia-Villoria J, Alston CL, Taylor RW, Briones P, Ribes A, Tort F. . Mitochondrion 2016, 26, 72-80.
  • Hall AM, Vilasi A, Garcia-Perez I, Lapsley M, Alston CL, Pitceathly RDS, McFarland R, Schaefer AM, Turnbull DM, Beaumont NJ, Hsuan JJ, Cutillas PR, Lindon JC, Holmes E, Unwin RJ, Taylor RW, Gorman GS, Rahman S, Hanna MG. . Kidney International 2015, 87(3), 610-622.
  • Hanisch F, Kornhuber M, Alston CL, Taylor RW, Deschauer M, Zierz S. . Journal of Neurology, Neurosurgery and Psychiatry 2015, 86(6), 630-634.
  • Gorman GS, Schaefer AM, Ng Y, Gomez N, Blakely EL, Alston CL, Feeney C, Horvath R, Yu-Wai-Man P, Chinnery PF, Taylor RW, Turnbull DM, McFarland R. . Annals of Neurology 2015, 77(5), 753-759.
  • Wesolowska M, Gorman GS, Alston CL, Pajak A, Pyle A, He L, Griffin H, Chinnery PF, Miller JAL, Schaefer AM, Taylor RW, Lightowlers RN, Chrzanowska-Lightowlers ZM. . Journal of Neuromuscular Diseases 2015, 2(4), 409-419.
  • Olahova M, Haack TB, Alston CL, Houghton JAC, He L, Morris AAM, Brown GK, McFarland R, Chrzanowska-Lightowlers ZMA, Lightowlers RN, Prokisch H, Taylor RW. . European Journal of Human Genetics 2015, 23(7), 935-939.
  • Alston CL, Berti CC, Blakely EL, Oláhová M, He L, McMahon CJ, Olpin SE, Hargreaves IP, Nolli C, McFarland R, Goffrini P, O'Sullivan MJ, Taylor RW. . Human Genetics 2015, 134(8), 869-879.
  • Keogh MJ, Daud D, Pyle A, Duff J, Griffin H, He L, Alston CL, Steele H, Taggart S, Basu AP, Taylor RW, Horvath R, Ramesh V, Chinnery PF. . Neurogenetics 2015, 16(1), 65-67.
  • Powell CA, Kopajtich R, D'Souza AR, Rorbach J, Kremer LS, Husain RA, Dallabona C, Donnini C, Alston CL, Griffin H, Pyle A, Chinnery PF, Strom TM, Meitinger T, Rodenburg RJ, Schottmann G, Schuelke M, Romain N, Haller RG, Ferrero I, Haack TB, Taylor RW, Prokisch H, Minczukl M. . American Journal of Human Genetics 2015, 97(2), 319-328.
  • Olahova M, Hardy SA, Hall J, Yarham JW, Haack TB, Wilson WC, Alston CL, He L, Aznauryan E, Brown RM, Brown GK, Morris AAM, Mundy H, Broomfield A, Barbosa IA, Simpson MA, Deshpande C, Moeslinger D, Koch J, Stettner GM, Bonnen PE, Prokisch H, Lightowlers RN, McFarland R, Chrzanowska-Lightowlers ZMA, Taylor RW. . Brain 2015, 138(12), 3503-3519.
  • Taylor RW, Pyle A, Griffin H, Blakely EL, Duff J, He LP, Smertenko T, Alston CL, Neeve VC, Best A, Yarham JW, Kirschner J, Schara U, Talim B, Topaloglu H, Baric I, Holinski-Feder E, Abicht A, Czermin B, Kleinle S, Morris AAM, Vassallo G, Gorman GS, Ramesh V, Turnbull DM, Santibanez-Koref M, McFarland R, Horvath R, Chinnery PF. . Journal of the American Medical Association 2014, 312(1), 68-77.
  • Pfeffer G, Gorman GS, Griffin H, Kurzawa-Akanbi M, Blakely EL, Wilson I, Sitarz K, Moore D, Murphy JL, Alston CL, Pyle A, Coxhead J, Payne B, Gorrie GH, Longman C, Hadjivassiliou M, McConville J, Dick D, Imam I, Hilton D, Norwood F, Baker MR, Jaiser SR, Yu-Wai-Man P, Farrell M, McCarthy A, Lynch T, McFarland R, Schaefer AM, Turnbull DM, Horvath R, Taylor RW, Chinnery PF. . Brain 2014, 137(5), 1323-1336.
  • Almalki A, Alston CL, Parker A, Simonic I, Mehta SG, He LP, Reza M, Oliveira JMA, Lightowlers RN, McFarland R, Taylor RW, Chrzanowska-Lightowlers ZMA. . Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease 2014, 1842(1), 56-64.
  • Blakely EL, Alston CL, Lecky B, Chakrabarti B, Falkous G, Turnbull DM, Taylor RW, Gorman GS. . Neuromuscular Disorders 2014, 24(6), 533-536.
  • Griffin HR, Pyle A, Blakely EL, Alston CL, Duff J, Hudson G, Horvath R, Wilson IJ, Santibanez-Koref M, Taylor RW, Chinnery PF. . Genetics in Medicine 2014, 16(12), 962-971.
  • Nesbitt V, Alston CL, Blakely EL, Fratter C, Feeney CL, Poulton J, Brown GK, Turnbull DM, Taylor RW, McFarland R. . European Journal of Human Genetics 2014, 22(11), 1255-1259.
  • Yarham JW, Blakely EL, Alston CL, Roberts ME, Ealing J, Pal P, Turnbull DM, McFarland R, Taylor RW. . Journal of the Neurological Sciences 2013, 325(1-2), 165-169.
  • Blakely EL, Yarham JW, Alston CL, Craig K, Poulton J, Brierley C, Park SM, Dean A, Xuereb JH, Anderson KN, Compston A, Allen C, Sharif S, Enevoldson P, Wilson M, Hammans SR, Turnbull DM, McFarland R, Taylor RW. . Human Mutation 2013, 34(9), 1260-1268.
  • Spyropoulos A, Manford M, Horvath R, Alston CL, Yu-Wai-Man P, He LP, Taylor RW, Chinnery PF. . JAMA Neurology 2013, 70(12), 1552-1555.
  • Lax NZ, Gnanapavan S, Dowson SJ, Alston CL, He LP, Polvikoski TM, Jaros E, O'Donovan DG, Yarham JW, Turnbull DM, Dean AF, Taylor RW. . Journal of Neuropathology and Experimental Neurology 2013, 72(2), 164-175.
  • Alston CL, Davison JE, Meloni F, van der Westhuizen FH, He LP, Hornig-Do HT, Peet AC, Gissen P, Goffrini P, Ferrero I, Wassmer E, McFarland R, Taylor RW. . Journal of Medical Genetics 2012, 49(9), 569-577.
  • Murphy JL, Ratnaike TE, Shang ES, Falkous G, Blakely EL, Alston CL, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. . Neuromuscular Disorders 2012, 22(8), 690-698.
  • Pitceathly RDS, Smith C, Fratter C, Alston CL, He LP, Craig K, Blakely EL, Evans JC, Taylor J, Shabbir Z, Deschauer M, Pohl U, Roberts ME, Jackson MC, Halfpenny CA, Turnpenny PD, Lunt PW, Hanna MG, Schaefer AM, McFarland R, Horvath R, Chinnery PF, Turnbull DM, Poulton J, Taylor RW, Gorman GS. . Brain 2012, 135(11), 3392-3403.
  • Pfeffer G, Blakely EL, Alston CL, Hassani A, Boggild M, Horvath R, Samuels DC, Taylor RW, Chinnery PF. . Journal of Neurology, Neurosurgery and Psychiatry 2012, 83(9), 883-886.
  • Alston CL, He LP, Morris AA, Hughes I, de Goede C, Turnbull DM, McFarland R, Taylor RW. . European Journal of Human Genetics 2011, 19(12), 1226-1229.
  • Yarham JW, Al-Dosary M, Blakely EL, Alston CL, Taylor RW, Elson JL, McFarland R. . Human Mutation 2011, 32(11), 1319-1325.
  • Alston CL, Bender A, Hargreaves IP, Mundy H, Deshpande C, Klopstock T, McFarland R, Horvath R, Taylor RW. . Neuromuscular Disorders 2010, 20(6), 403-406.
  • Tuppen HA, Hogan VE, He L, Blakely EL, Worgan L, Al-Dosary M, Saretzki G, Alston CL, Morris AA, Clarke M, Jones S, Devlin AM, Mansour S, Chrzanowska-Lightowlers ZMA, Thorburn DR, McFarland R, Taylor RW. . Brain 2010, 133(10), 2952-2963.
  • Blackwood JK, Whittaker RG, Blakely EL, Alston CL, Turnbull DM, Taylor RW. . Biochemical and Biophysical Research Communications 2010, 393(4), 740-745.
  • Alston CL, Lowe J, Turnbull DM, Maddison P, Taylor RW. . Journal of the Neurological Sciences 2010, 298(1-2), 140-144.
  • Alston CL, Morak M, Reid C, Hargreaves IP, Pope SAS, Land JM, Heales SJ, Horvath R, Mundy H, Taylor RW. . Neuromuscular Disorders 2010, 20(2), 131-135.

• Book Chapter

  • Deen D, Alston CL, Hudson G, Taylor RW, Pyle A. . In: Nicholls TJ; Uhler JP; Falkenberg M, ed. Mitochondrial DNA. New York: Humana Press, Inc, 2023, pp.397-425.

• Conference Proceedings (inc. Abstracts)

  • Van Coster R, Smet J, De Paepe B, Vanlander A, Vantroys E, Alston C, Compton A, Torburn D, Seneca S, Taylor R. . In: 21st International Congress of the World Muscle Society. 2016, Granada, Spain: Elsevier Ltd.
  • Craven L, Irving L, Alston CL, Watson EL, Byerley S, McFarland R, Stewart JA, Taylor RW, Herbert M, Turnbull DM. . In: 13th Annual Preimplantation Genetic Diagnosis International Society (PGDIS) Meeting. 2014, Canterbury, UK: Springer.
  • Byerley SK, Blakely EW, Alston CL, Turnbull DM, Stewart JA, McFarland R, Taylor RW, Herbert M. . In: 13th Annual Preimplantation Genetic Diagnosis International Society (PGDIS) Meeting. 2014, Canterbury, UK: Springer.
  • Ng Y, Alston C, Horvath R, Farrugia M, Chinnery P, Turnbull D, Taylor R, McFarland R, Schaefer A, Gorman G. . In: Association of British Neurologists Annual Meeting. 2014, Cardiff: BMJ Publishing Group.

• Editorials

  • Alston CL, Schaefer AM, Raman P, Solaroli N, Krishnan KJ, Blakely EL, He LP, Craig K, Roberts M, Vyas A, Nixon J, Horvath R, Turnbull DM, Karlsson A, Gorman GS, Taylor RW. . Neurology 2013, 81(23), 2051-2053.
  • Whittaker RG, Blackwood JK, Alston CL, Blakely EL, Elson JL, McFarland R, Chinnery PF, Turnbull DM, Taylor RW. . Neurology 2009, 72(6), 568-569.

• Letters

  • Alston CL, Blakely EL, McFarland R, Taylor RW. . Journal of the Neurological Sciences 2020, 417, 116950.
  • Kullar P, Taylor RW, Alston CL, Blakely EL, Ball S, Differ A-M, Fratter C, Sweeney MG, Chinnery PF. . Hearing, Balance and Communication 2016, 14(2), 101-102.
  • Bates MG, Nesbitt V, Kirk R, He L, Blakely EL, Alston CL, Brodlie M, Hasan A, Taylor RW, McFarland R. . International Journal of Cardiology 2012, 155(2), 305–306.

• Reviews

  • Alston CL, Stenton SL, Hudson G, Prokisch H, Taylor RW. . Journal of Pathology 2021, 254(4), 430-442.
  • Fullerton M, McFarland R, Taylor RW, Alston CL. . Molecular Genetics and Metabolism 2020, 131(1-2), 53-65.
  • Thompson K, Collier JJ, Glasgow RIC, Robertson FM, Pyle A, Blakely EL, Alston CL, Olahova M, McFarland R, Taylor RW. . Journal of Inherited Metabolic Disease 2020, 43(1), 36-50.
  • Nesbitt V, Morrison PJ, Crushell E, Donnelly DE, Alston CL, He LP, Mcfarland R, Taylor RW. . Developmental Medicine and Child Neurology 2012, 54(6), 500-506.
  • Alston C. . Slavonic and East European Review 2003, 81(2), 362-363.