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Staff Profile

Professor Derek Mann

Professor of Hepatology

  • Telephone: +44 (0) 191 208 3851
  • Personal Website: /medicalsciences/research/groups/liver/
  • Address: Â鶹´«Ã½ Fibrosis Research Group
    4th Floor, William Leech Building
    Medical School
    Â鶹´«Ã½
    NE2 4HH
Background

Introduction

I am Professor of Hepatology with a specific interest in the biology of liver disease and cancer, and to deliver pre-clinical research that directly translates to clinical studies. Ongoing work of my team and in collaboration with colleagues at the CRUK Scotland Centre in Glasgow is funded by a renewed CRUK programme grant that is focused on the manipulation of neutrophils as a means to enhance immunotherapy of hepatocellular carcinoma. The most recent work of my team has laid the foundations for an ongoing CRUK funded clinical trial using the CXCR2 inhibitor AZD5069 in combination with durvalumab (anti-PD-L1) in advanced hepatocellular carcinoma (HCC) with the concept that this treatment converts neutrophils from a pro- to anti-tumour phenotype. In addition we are designing ex-vivo and in vitro models of HCC to enable improved drug discovery platforms that recapitulate the complex multicelllular nature of the HCC tumour microenvironment. My team is also currently funded by an MRC grant to investigate mechanisms by which cellular senescence promotes liver steatosis and inflammation. My previous work on the epigenetic and transcriptional control of liver fibrosis was the basis for my election to Fellowship of the Academy of Medical Sciences in 2017. I am currently a member of external grant reviewing panels for the MRC and Yorkshire Cancer Research, and a founding scientist and director of FirboFind Ltd.

Research

Research Interests

Tissue fibrosis, Inflammation, Ageing, Cancer.

Gene regulation (epigenetic and transcriptional)

Cell biology of myofibroblasts and neutrophils.

Current Work

Discovery of therapies for the prevention and treatment of chronic liver disease and cancer.

Discovery of biomarkers and therapeutic targets for tissue fibrosis.

Understanding the basic regulatory mechanisms that control cell phenotype, function and fate with the emphasis on events at the level of gene transcription.

Research Roles

Group Leader

Postgraduate Supervision

Currently supervise several PhD students

Esteem Indicators

Fellow of the Academy of Medical Sciences (2017)

Funding

GSK Programme.

8-year pre-clinical research programme aimed at discovering biomarkers of fibrosis and advancing anti-fibrotics into clinical studies. £1.4M. 2011 – 2019. Mann is PI.  

  

 NIAAA (NIH) UO1 Collaborator Programme Grant.

Epigenetic regulation of alcoholic liver fibrosis. $2M. 2016 - 2021. Mann is joint PI.

 

MRC/Â鶹´«Ã½ Lifelong Health and Wellbeing Centre for Ageing and Vitality. £3,500,000. 2015-2020. Mann is Co-Director (Sir Doug Turnbull is Director).

 

EU Collaborative Grant.

Elucidating Pathways of Steatohepatitis. Euros 6M. 2015-2019. Mann named

investigator.

 

Abbvie. Collaborative research investigating mechanisms of fibrosis in non-alcoholic fatty liver disease. 2016-2018. £594,195. Mann is PI.

 

Abbvie. Collaborative research aimed at identifying biomarkers that predict fibrosis progression in non-alcoholic fatty liver disease. 2016-2018. £597,701. Mann is Co-I.

 

Cancer Research UK (CRUK) Programme Grant.

Towards targeting neutrophils in hepatocellular carcinoma. 2017-2021. £1,740,000. Mann is joint PI.


MRC MICA Programme Grant (in collaboration with GSK).

Molecular drivers of fibrosis at the hepatic epithelial-mesenchymal barrier. circa-£2M.

2018-2022. Mann is PI.

Industrial Relevance

Funded collaborations with GSK and Abbvie.

Patents

US200519130
WO2004019921
W02006072783
EP1531825

Publications

  • Articles

    • Collins A, Scott R, Wilson CL, Abbate G, Ecclestone GB, Albanese AG, Biddles D, White S, French J, Moir J, Alrawashdeh W, Wilson C, Pandanaboyana S, Hammond JS, Thakkar R, Oakley F, Mann J, Mann DA, Kenneth NS. . Bioscience Reports 2024, 44(6), BSR20232147.
    • Lockhart SM, Muso M, Zvetkova I, Lam BYH, Ferrari A, Schoenmakers E, Duckett K, Leslie J, Collins A, Romartinez-Alonso B, Tadross JA, Jia R, Gardner EJ, Kentistou K, Zhao Y, Day F, Morseburg A, Rainbow K, Rimmington D, Mastantuoni M, Harrison J, Nus M, Guma'a K, Sherratt-Mayhew S, Jiang X, Smith KR, Paul DS, Jenkins B, Koulman A, Pietzner M, Langenberg C, Wareham N, Yeo GS, Chatterjee K, Schwabe J, Oakley F, Mann DA, Tontonoz P, Coll AP, Ong K, Perry JRB, O'Rahilly S. . Nature Metabolism 2024, 6, 1922-1938.
    • Rimmer L, Mann D, Sayer AA, Amarnath S, Granic A. . Frontiers in Immunology 2024, 15, 1360141.
    • Orange ST, Leslie J, Ross M, Mann DA, Wackerhage H. . Trends in Endocrinology and Metabolism 2023, 34(11), 749-763.
    • Vucur M, Ghallab A, Schneider AT, Adili A, Cheng M, Castoldi M, Singer MT, Buttner V, Keysberg LS, Kusgens L, Kohlhepp M, Gorg B, Gallage S, Barragan Avila JE, Unger K, Kordes C, Leblond A-L, Albrecht W, Loosen SH, Lohr C, Jordens MS, Babler A, Hayat S, Schumacher D, Koenen MT, Govaere O, Boekschoten MV, Jors S, Villacorta-Martin C, Mazzaferro V, Llovet JM, Weiskirchen R, Kather JN, Starlinger P, Trauner M, Luedde M, Heij LR, Neumann UP, Keitel V, Bode JG, Schneider RK, Tacke F, Levkau B, Lammers T, Fluegen G, Alexandrov T, Collins AL, Nelson G, Oakley F, Mann DA, Roderburg C, Longerich T, Weber A, Villanueva A, Samson AL, Murphy JM, Kramann R, Geisler F, Costa IG, Hengstler JG, Heikenwalder M, Luedde T. . Immunity 2023, 56(7), 1578-1595.e8.
    • Sabater L, Gossart JB, Hernandez I, Rico D, Blanchard A, Borthwick LA, Fisher AJ, Majo J, Jiwa K, Collins A, Abbate G, Oakley F, Mann DA, Mann J. . American Journal of Pathology 2023, 193(4), 417-429.
    • Zadran B, Sudhindar PD, Wainwright D, Bury Y, Luli S, Howarth R, McCain MV, Watson R, Huet H, Palinkas F, Palmini RB, Casement J, Mann DA, Oakley F, Lunec J, Reeves H, Faulkner GJ, Shukla R. . British Journal of Cancer 2023, 128, 1236-1248.
    • Leslie J, Hunter JE, Collins A, Rushton A, Russell LG, Ramon-Gil E, Laszczewska M, McCain M, Zaki MYW, Knox A, Seow Y, Sabater L, Geh D, Perkins ND, Reeves HL, Tiniakos D, Mann DA, Oakley F. . Hepatology 2023, 78(4), 1050-1063.
    • Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. . Nature 2023, 622, 627-636.
    • Labiano I, Agirre-Lizaso A, Olaizola P, Echebarria A, Huici-Izagirre M, Olaizola I, Esparza-Baquer A, Sharif O, Hijona E, Milkiewicz P, Milkiewicz M, Gonzalez-Romero F, Aspichueta P, Monte MJ, Marin JJG, Vucur M, Luedde T, Marzioni M, Mann DA, Bujanda L, Rodrigues PM, Banales JM, Perugorria MJ. . Journal of Hepatology 2022, 77(4), 991-1004.
    • Leslie J, Mackey JBG, Jamieson T, Ramon-Gil E, Drake TM, Fercoq F, Clark W, Gilroy K, Hedley A, Nixon C, Luli S, Laszczewska M, Pinyol R, Esteban-Fabro R, Willoughby CE, Haber PK, Andreu-Oller C, Rahbari M, Fan C, Pfister D, Raman S, Wilson N, Muller M, Collins A, Geh D, Fuller A, Mcdonald D, Hulme G, Filby A, Cortes-Lavaud X, Mohamed N-E, Ford CA, Raffo Iraolagoitia XL, Mcfarlane AJ, Mccain MV, Ridgway RA, Roberts EW, Barry ST, Graham GJ, Heikenwalder M, Reeves HL, Llovet JM, Carlin LM, Bird TG, Sansom OJ, Mann DA. . Gut 2022, 71(10), 2093-2106.
    • Esparza-Baquer A, Labiano I, Sharif O, Agirre-Lizaso A, Oakley F, Rodrigues PM, Zhuravleva E, O'Rourke CJ, Hijona E, Jimenez-Agüero R, Riaño I, Landa A, La Casta A, Zaki MYW, Munoz-Garrido P, Azkargorta M, Elortza F, Vogel A, Schabbauer G, Aspichueta P, Andersen JB, Knapp S, Mann DA, Bujanda L, Banales JM, Perugorria MJ. . Gut 2021, 70(7), 1345-1361.
    • Lagnado A, Leslie J, Ruchaud-Sparagano MH, Victorelli S, Hirsova P, Ogrodnik M, Collins AL, Grazia Vizioli M, Habiballa L, Saretzki G, Evans SA, Salmonowicz H, Hruby A, Geh D, Pavelko KD, Dolan D, Reeves HL, Grellscheid S, Wilson CH, Pandanaboyana S, Doolittle M, Von Zglinicki T, Oakley F, Gallage S, Wilson CL, Birch J, Carroll B, Chapman J, Heikenwalder M, Neretti N, Khosla S, Masuda CA, Tchkonia T, Kirkland JL, Jurk D, Mann DA, Passos JF. . The EMBO Journal 2021, 40(9), e106048.
    • Bianchi A, Marchetti L, Hall Z, Lemos H, Vacca M, Paish H, Green K, Elliott B, Tiniakos D, Passos JF, Jurk D, Mann DA, Wilson CL. . Journal of Immunology 2021, 206(4), 904-916.
    • Zaki MYW, Mahdi AK, Patman GL, Whitehead A, Mauricio JP, McCain MV, Televantou D, Abou-Beih S, Ramon-Gil E, Watson R, Cox C, Leslie J, Wilson C, Govaere O, Lunec J, Mann DA, Nakjang S, Oakley F, Shukla R, Anstee QM, Tiniakos D, Reeves HL. . Scientific Reports 2021, 11(1), 16727.
    • SiejkaZielinska P, Cheng J, Jackson F, Liu Y, Soonawalla Z, Reddy S, Silva M, Puta L, McCain MV, Culver E, Bekkali N, SchusterBockler B, Palamara PF, Mann D, Reeves H, Barnes E, Sivakumar S, Song C. . Science Advances 2021, 7(36).
    • Garcia-Macia M, Santos-Ledo A, Leslie J, Paish HL, Collins AL, Scott RS, Watson A, Burgoyne RA, White S, French J, Hammond J, Borthwick LA, Mann J, Bolanos JP, Korolchuk VI, Oakley F, Mann DA. . Hepatology 2021, 74(6), 3441-3459.
    • Sabater L, Locatelli L, Oakley F, Hardy T, French J, Robinson SM, Sen G, Mann DA, Mann J. . Scientific Reports 2020, 10(1), 21708.
    • Attard V, Li CY, Self A, Mann DA, Borthwick LA, O'Connor P, Deehan DJ, Kalson NS. . Bone and Joint Journal 2020, 102(10), 1331-1340.
    • Ball SL, Cockell SJ, Wilson JA, Mann DA, Fisher AJ. . Rhinology 2020, 58(6), 581-587.
    • Leslie J, Millar BJM, del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson JA, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. . JCI Insight 2020, 5(4), e125937.
    • Leslie J, Garcia Macia M, Luli S, Worrell JC, Reilly W, Paish HL, Knox A, Barksby BS, Gee LM, Zaki MYW, Collins A, Burgoyne RA, Cameron R, Bragg C, Xu X, Chung GW, Brown CDA, Blanchard AD, Nanthakumar CB, Karsdal M, Robinson SM, Manas DM, Sen G, French J, White SA, Murphy S, Trost M, Zakrzewski JL, Klein U, Schwabe RF, Mederacke I, Nixon C, Bird T, Teuwen LA, Schoonjans L, Carmeliet P, Mann J, Fisher AJ, Sheerin NS, Borthwick LA, Mann DA, Oakley F. . Nature Metabolism 2020, 2, 1350-1367.
    • Worrell J, Leslie J, Smith GR, Zaki M, Paish H, Knox A, James ML, Cartwright TN, OReily S, Kania G, Distler O, Distler J, Herrick A, Jeziorska M, Borthwick LA, Fisher AJ, Mann J, Mann DA, Oakley F. . Rheumatology 2020, 59(12), 3939-3951.
    • Fielder E, Tweedy C, Wilson C, Oakley F, LeBeau FEN, Passos JF, Mann DA, von Zglinicki T, Jurk D. . Aging Cell 2020, 19(10), e13188.
    • CorreiaMelo C, Birch J, Fielder E, Rahmatika D, Taylor J, Chapman J, Lagnado A, Carroll BM, Miwa S, Richardson G, Jurk D, Oakley F, Mann J, Mann DA, Korolchuk V, Passos JF. . Aging Cell 2019, 18(1), e12882.
    • Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. . Nature Medicine 2019, 25(4), 641-655.
    • Perugorria MJ, Esparza-Baquer A, Oakley F, Labiano I, Korosec A, Jais A, Mann J, Tiniakos D, Santos-Laso A, Arbelaiz A, Gawish R, Sampedro A, Fontanellas A, Hijona E, Jimenez-Aguero R, Esterbauer H, Stoiber D, Bujanda L, Banales JM, Knapp S, Sharif O, Mann DA. . Gut 2019, 68(3), 533-546.
    • Moran-Salvador E, Garcia-Macia M, Sivaharan A, Sabater L, Zaki MYW, Oaklet F, Knox A, Page A, Luli S, Mann J, Mann DA. . Gastroenterology 2019, 157(5), 1398-1412.e9.
    • Paish HL, Baldock TE, Gillespie CS, del Carpio Pons A, Mann DA, Deehan DJ, Borthwick LA, Kalson NS. . Journal of Orthopaedic Research 2019, 37(11), 2316-2324.
    • Paish H, Reed L, Brown H, Bryan M, Govaere O, Leslie J, Barksby B, GarciaMacia M, Watson A, Xu X, Zaki M, Greaves L, Whitehall J, French J, White S, Manas D, Robinson S, Spoletini G, Griffiths C, Mann DA, Borthwick LA, Drinnan M, Mann J, Oakley F. . Hepatology 2019, 70(4), 1377-1391.
    • Kalson NS, Brock TM, Mangino M, Fabiane SM, Mann DA, Borthwick LA, Deehan DJ, Williams FMK. . PLoS ONE 2018, 13(1), e0190120.
    • Yigit B, Boyle M, Ozler O, Erden N, Tutucu F, Hardy T, Bergmann C, Distler JHW, Adali G, Dayangac M, Mann DA, Zeybel M, Mann J. . Gut 2018, 67(10), 1907-1908.
    • Margetts J, Ogle LF, Chan SL, Chan AWH, Chan KCA, Jamieson D, Willoughby CE, Mann DA, Wilson CL, Manas DM, Yeo W, Reeves HL. . British Journal of Cancer 2018, 118, 248-257.
    • Cartwright TN, Worrell JC, Marchetti L, Dowling CM, Knox A, Kiely P, Mann J, Mann DA, Wilson CL. . Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2018, 1861(10), 962-970.
    • Paish HL, Kalson NS, Smith GR, del Carpio Pons A, Baldock TE, Smith N, Swist-Szulik K, Weir DJ, Bardgett M, Deehan DJ, Mann DA, Borthwick LA. . American Journal of Pathology 2018, 188(3), 696-714.
    • Madakashira B, Corbett L, Zhang C, Paoli P, Casement JW, Mann J, Sadler KC, Mann DA. . Epigenetics 2017, 12(9), 811-824.
    • Fearn A, Situmorang GR, Fox C, Oakley F, Howarth R, Wilson CL, Kiosia A, Robson MG, Mann DA, Moles A, Sheerin NS. . Cell Death and Disease 2017, 8, e2883.
    • Wettstein G, Luccarini JM, Poekes L, Faye P, Kupkowski F, Adarbes V, Defrêne E, Estivalet C, Gawronski X, Jantzen I, Philippot A, Tessier J, TuyaaBoustugue P, Oakley F, Mann DA, Leclercq I, Francque S, Konstantinova I, Broqua P, Junien JL. . Hepatology Communications 2017, 1(6), 524-537.
    • Hardy T, Zeybel M, Day CP, Dipper C, Masson S, McPherson S, Henderson E, Tiniakos D, White S, French J, Mann DA, Anstee QM, Mann J. . Gut 2017, 66(7), 1321-1328.
    • Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Nagaraja Grellscheid S, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. . Nature Communications 2017, 8, 15691.
    • McPherson S, Wilkinson N, Tiniakos D, Wilkinson J, Burt AD, McColl E, Stocken DD, Steen N, Barnes J, Goudie N, Stewart S, Bury Y, Mann D, Anstee QM, Day CP. . PLoS One 2017, 12(4), e0175717.
    • Zeybel M, Luli S, Sabater L, Hardy T, Oakley F, Leslie J, Page A, Salvador EM, Sharkey V, Tsukamoto H, Chu DCK, Singh US, Ponzoni M, Perri P, Di Paolo D, Mendivil EJ, Mann J, Mann DA. . Molecular Therapy 2017, 25(1), 218-231.
    • Vyrla D, Nikolaidis G, Oakley F, Perugorria MJ, Tsichlis PN, Mann DA, Eliopoulos AG. . Journal of Immunology 2016, 196(10), 4298-4310.
    • Ball SL, Mann DA, Wilson JA, Fisher AJ. . American Journal of Pathology 2016, 186(2), 225-233.
    • Correia-Melo C, Marques FDM, Anderson R, Hewitt G, Hewitt R, Cole J, Carroll BM, Miwa S, Birch J, Merz A, Rushton MD, Charles M, Jurk D, Tait SWG, Czapiewski R, Greaves L, Nelson G, Bohlooly-Y M, Rodriguez-Cuenca S, Vidal-Puig A, Mann D, Saretzki G, Quarato G, Green DR, Adams PD, von Zglinicki T, Korolchuk VI, Passos JF. . EMBO Journal 2016, 35(7), 724-742.
    • Kalson NS, Borthwick LA, Mann DA, Deehan DJ, Lewis P, Mann C, Mont MA, Morgan-Jones R, Oussedik S, Williams FMK, Toms A, Argenson JN, Bellemans J, Bhave A, Furnes O, Gollwitzer J, Haddad FS, Hofmann S, Krenn V. . Bone & Joint Journal 2016, 98-B(11), 1479-1488.
    • Lanucara F, Lam C, Mann J, Monie TP, Colombo SAP, Holman SW, Boyd J, Dange MC, Mann DA, White MRH, Eyers CE. . Open Biology 2016, 6(7).
    • Moles A, Butterworth JA, Sanchez A, Hunter JE, Leslie J, Sellier H, Tiniakos D, Cockell SJ, Mann DA, Oakley F, Perkins ND. . Oncogene 2016, 35(35), 4623-4632.
    • Luli S, Di Paolo D, Perri P, Brignole C, Hill SJ, Brown H, Leslie J, Marshall HL, Wright MC, Mann DA, Ponzoni M, Oakley F. . Journal of Hepatology 2016, 65(1), 75-83.
    • Borthwick LA, Suwara MI, Carnell SC, Green NJ, Mahida R, Dixon D, Gillespie CS, Cartwright TN, Horabin J, Walker A, Olin E, Rangar M, Gardner A, Mann J, Corris PA, Mann DA, Fisher AJ. . American Journal of Transplantation 2016, 16(6), 1751-1765.
    • Wilson CL, Murphy LB, Leslie J, Kendrick S, French J, Fox CR, Sheerin NS, Fisher A, Robinson JH, Tiniakos DG, Gray DA, Oakley F, Mann DA. . Journal of Hepatology 2015, 63(6), 1421-1428.
    • Corbett L, Mann J, Mann DA. . PLoS ONE 2015, 10(11), e0142794.
    • Wilson CL, Jurk D, Fullard N, Banks P, Page A, Luli S, Elsharkawy AM, Gieling RG, Bagchi-Chakraborty J, Fox C, Richardson C, Callaghan K, Blair GE, Fox N, Lagnado A, Passos JF, Moore AJ, Smith GR, Tiniakos DG, Mann J, Oakley F, Mann DA. . Nature Communications 2015, 6, 6818.
    • Williams FM, Kalson NS, Fabiane SM, Mann DA, Deehan DJ. . PLoS ONE 2015, 10(7), e0133629.
    • Ball SL, Suwara MI, Borthwick LA, Wilson JA, Mann DA, Fisher AJ. . Annals of Otology, Rhinology & Laryngology 2015, 124(6), 437-442.
    • Abdul N, Dixon D, Walker A, Horabin J, Smith N, Weir DJ, Brewster NT, Deehan DJ, Mann DA, Borthwick LA. . Scientific Reports 2015, 5, 16469.
    • Page A, Paoli PP, Hill SJ, Howarth R, Wu R, Kweon SM, French J, White S, Tsukamoto H, Mann DA, Mann J. . Journal of Hepatology 2015, 62(2), 388-397.
    • Dixon D, Coates J, Pons AD, Horabin J, Walker A, Abdul N, Kalson NS, Brewster NT, Weir DJ, Deehan DJ, Mann DA, Borthwick LA. . Scientific Reports 2015, 5, 16466.
    • Wilson CL, Mann J, Walsh M, Perrugoria MJ, Oakley F, Wright MC, Brignole C, Di Paolo D, Perri P, Ponzoni M, Karin M, Mann DA. . PLoS One 2014, 9(1), e83391.
    • Suwara MI, Green NJ, Borthwick LA, Mann J, Mayer-Barber KD, Barron L, Corris PA, Farrow SN, Wynn TA, Fisher AJ, Mann DA. . Mucosal Immunology 2014, 7(3), 684-693.
    • Jurk D, Wilson C, Passos J, Oakley F, Correia-Melo C, Greaves L, Saretzki G, Fox C, Lawless C, Anderson R, Hewitt G, Pender SLF, Fullard N, Nelson G, Mann J, van de Sluis B, Mann DA, von Zglinicki T. . Nature Communications 2014, 5, 4172.
    • Moles A, Murphy L, Wilson CL, Bagchi Chakraborty J, Fox C, Park EJ, Mann J, Oakley F, Howarth R, Brain J, Masson S, Karin M, Seki E, Mann DA. . Journal of Hepatology 2014, 60(4), 782-791.
    • Probert PME, Ebrahimkhani MR, Oakley F, Mann J, Burt AD, Mann DA, Wright MC. . Toxicology Research 2014, 3(2), 98-109.
    • Perugorria MJ, Murphy LB, Fullard N, Chakraborty JB, Vyrla D, Wilson CL, Oakley F, Mann J, Mann DA. . Hepatology 2013, 57(3), 1238-1249.
    • Borthwick LA, Corris PA, Mahida R, Walker A, Gardner A, Suwara M, Johnson GE, Moisey EJ, Brodlie M, Ward C, Perry JD, de Soyza A, Mann DA, Fisher AJ. . American Journal of Transplantation 2013, 13(3), 621-633.
    • Robinson SM, Mann DA, Manas DM, Oakley F, Mann J, White SA. . British Journal of Cancer 2013, 109(9), 2396-2403.
    • Fullard N, Moles A, O'Reilly S, van Laar JM, Faini D, Diboll J, Reynolds NJ, Mann DA, Reichelt J, Oakley F. . American Journal of Pathology 2013, 182(6), 2109-2120.
    • Robinson SM, Mann J, Vasilaki A, Mathers J, Burt AD, Oakley F, White SA, Mann DA. . Journal of Hepatology 2013, 59(2), 318-326.
    • Moles A, Sanchez AM, Banks PS, Murphy LB, Luli S, Borthwick L, Fisher A, O'Reilly S, van Laar JM, White SA, Perkins ND, Burt AD, Mann DA, Oakley F. . Hepatology 2013, 57(2), 817-828.
    • Robinson SM, Mann J, Manas DM, Mann DA, White SA. . HPB 2013, 15(8), 581-587.
    • Borthwick LA, Gardner A, De Soyza A, Mann DA, Fisher AJ. . Cancer Microenvironment 2012, 5(1), 45-57.
    • Borthwick LA, Gardner A, De-Soyza A, Mann DA, Fisher AJ. . Cancer Microenvironment 2012, 5(1), 45-57.
    • Richter C, Messerschmidt S, Holeiter G, Tepperink J, Osswald S, Zappe A, Branschädel M, Boschert V, Mann DA, Scheurich P, Krippner-Heidenreich A. . Molecular and Cellular Biology 2012, 32(13), 2515-2529.
    • Gaspar-Pereira S, Fullard N, Townsend PA, Banks PS, Ellis EL, Fox C, Maxwell AG, Murphy LB, Kirk A, Bauer R, Caamaño JH, Figg N, Foo RS, Mann J, Mann DA, Oakley F. . American Journal of Pathology 2012, 180(3), 929-939.
    • Gardner A, Fisher AJ, Richter C, Johnson GE, Moisey EJ, Brodlie M, Ward C, Krippner-Heidenreich A, Mann DA, Borthwick LA. . American Journal of Pathology 2012, 180(6), 2293-2308.
    • Westenberg M, Soedling HM, Hirani N, Nicholson LJ, Mann DA, Dolphin CT. . Journal of General Virology 2012, 93(7), 1583-1590.
    • Yang MD, Chiang YM, Higashiyama R, Asahina K, Mann DA, Mann J, Wang CCC, Tsukamoto H. . Hepatology 2012, 55(4), 1271-1281.
    • Pritchett J, Harvey E, Athwal V, Berry A, Rowe C, Oakley F, Moles A, Mann DA, Bobola N, Sharrocks AD, Thomson BJ, Zaitoun AM, Irving WL, Guha IN, Hanley NA, Hanley KP. . Hepatology 2012, 56(3), 1108-1116.
    • Zeybel M, Hardy T, Wong YK, Mathers JC, Fox CR, Gackowska A, Oakley F, Burt AD, Wilson CL, Anstee QM, Barter MJ, Masson S, Elsharkawy AM, Mann DA, Mann J. . Nature Medicine 2012, 18(9), 1369-U110.
    • Perugorria MJ, Wilson CL, Zeybel M, Walsh M, Amin S, Robinson S, White SA, Burt AD, Oakley F, Tsukamoto H, Mann DA, Mann J. . Hepatology 2012, 56(3), 1129-1139.
    • Amin S, Walsh M, Wilson C, Parker AE, Oscier D, Willmore E, Mann D, Mann J. . Journal of Cellular and Molecular Medicine 2012, 16(9), 2074-2084.
    • Ebrahimkhani MR, Oakley F, Murphy LB, Mann J, Moles A, Perugorria MJ, Ellis E, Lakey AF, Burt AD, Douglass A, Wright MC, White SA, Jaffre F, Maroteaux L, Mann DA. . Nature Medicine 2011, 17(12), 1668-U189.
    • Nakachi S, Nakazato T, Ishikawa C, Kimura I, Mann DA, Senba M, Masuzaki H, Mori N. . Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2011, 1813(5), 731-741.
    • Wallace K, Cowie DE, Konstantinou DK, Hill SJ, Tjelle TE, Axon A, Koruth M, White SA, Carlsen H, Mann DA, Wright MC. . Journal of Steroid Biochemistry and Molecular Biology 2010, 120(2-3), 137-148.
    • Elsharkawy AM, Oakley F, Lin F, Packham G, Mann DA, Mann J. . Journal of Hepatology 2010, 53(3), 519-527.
    • Gieling RG, Elsharkawy AM, Caamano JH, Cowie DE, Wright MC, Ebrahimkhani MR, Burt AD, Mann J, Raychaudhuri P, Liou HC, Oakley F, Mann DA. . Hepatology 2010, 51(3), 922-931.
    • Yang CB, Atkinson SP, Vilella F, Lloret M, Armstrong L, Mann DA, Lako M. . Stem Cells 2010, 28(11), 1970-1980.
    • Chakraborty JB, Mann DA. . Journal of Hepatology 2010, 52(2), 285-291.
    • Mann J, Chu DCK, Maxwell A, Oakley F, Zhu NL, Tsukamoto H, Mann DA. . Gastroenterology 2010, 138(2), 705-714.
    • Westenberg M, Soedling HM, Mann DA, Nicholson LJ, Dolphin CT. . Nucleic Acids Research 2010, 38(16), e166.
    • Potter C, Cordell HJ, Barton A, Daly AK, Hyrich K, Mann D, Morgan A, Wilson AG, and the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Isaacs J. . Annals of the Rheumatic Diseases 2010, 69(7), 1315-1320.
    • Souslova V, Townsend PA, Mann J, van der Loos CM, Motterle A, D'Acquisto F, Mann DA, Ye S. . PLoS ONE 2010, 5(3), -.
    • Guo JS, Hong F, Loke J, Yea S, Lim CL, Lee U, Mann DA, Walsh MJ, Sninsky JJ, Friedman SL. . Journal of Biological Chemistry 2010, 285(8), 5428-5437.
    • Mann J, Mann DA. . Advanced Drug Delivery Reviews 2009, 61(7-8), 497-512.
    • Gieling RG, Elsharkawy AM, Cowie D, Raychaudhuri P, Caamano JH, Oakley F, Mann DA. . Journal of Hepatology 2009, 50, S310-S311.
    • Kudo H, Yata Y, Takahara T, Kawai K, Nakayama Y, Kanayama M, Oya T, Morita S, Sasahara M, Mann DA, Sugiyama T. . Liver International 2009, 29(7), 988-996.
    • Oakley F, Teoh V, Ching-A-Sue G, Bataller R, Colmenero J, Jonsson JR, Eliopoulos AG, Watson MR, Manas D, Mann DA. . Gastroenterology 2009, 136(7), 2334-2344.
    • Hartland SN, Murphy F, Aucott RL, Abergel A, Zhou X, Waung J, Patel N, Bradshaw C, Collins J, Mann D, Benyon RC, Iredale JP. . Liver International 2009, 29(7), 966-978.
    • Ruddell RG, Mann DA, Ramm GA. . Journal of Hepatology 2008, 48(4), 666-675.
    • Watson MR, Wallace K, Gieling RG, Manas DM, Jaffray E, Hay RT, Mann DA, Oakley F. . Journal of Hepatology 2008, 48(4), 589-597.
    • Campbell SJ, Anthony DC, Oakley F, Carlsen H, Elsharkawy AM, Blomhoff R, Mann DA. . Journal of Neuropathology and Experimental Neurology 2008, 67(3), 223-230.
    • Gieling R, Burt AD, Mann DA. . Clinics in Liver Disease 2008, 12(4), 915-937.
    • Hanley KP, Oakley F, Sugden S, Wilson DI, Mann DA, Hanley NA. . Journal of Biological Chemistry 2008, 283(20), 14063-14071.
    • Hagens WI, Beljaars L, Mann DA, Wright MC, Julien B, Lotersztajn S, Reker-Smit C, Poelstra K. . Journal of Pharmacology and Experimental Therapeutics 2008, 324(3), 902-910.
    • Mann J, Oakley F, Akiboye F, Elsharkawy A, Thorne AW, Mann DA. . Cell Death and Differentiation 2007, 14(2), 275-285.
    • Haughton EL, Tucker SJ, Marek CJ, Durward E, Leel V, Bascal Z, Monaghan T, Koruth M, Collie-Duguid E, Mann DA, Trim JE, Wright MC. . Gastroenterology 2006, 131(1), 194-209.
    • Pickering BM, Mel Sde, Lee M, Howell M, Habens F, Dallman CL, Neville LA, Potter KN, Mann J, Mann DA, Johnson PW, Stevenson FK, Packham G. . Oncogene 2006, 26(8), 1167-1177.
    • Ebrahimkhani MR, Kiani S, Oakley F, Kendall T, Shariftabrizi A, Tavangar SM, Moezi L, Payabvash S, Karoon A, Hoseininik H, Mann DA, Moore KP, Mani AR, Dehpour AR. . Gut 2006, 55(11), 1606-1616.
    • Smart DE, Green K, Oakley F, Weitzman JB, Yaniv M, Reynolds G, Mann J, Millward-Sadler H, Mann DA. . Hepatology 2006, 44(6), 1432-1440.
    • Ruddell RG, Oakley F, Hussain Z, Yeung I, Bryan-Lluka LJ, Ramm GA, Mann DA. . American Journal of Pathology 2006, 169(3), 861-876.
    • Elsharkawy AM, Oakley F, Mann DA. . Apoptosis 2005, 10(5), 927-939.
    • Nicholson LJ, Philippe M, Paine AJ, Mann DA, Dolphin CT. . Molecular Therapy 2005, 11(4), 638-644.
    • Oakley F, Mann J, Nailard S, Smart DE, Mungalsingh N, Constandinou C, Ali S, Wilson SJ, Millward-Sadler H, Iredale JP, Mann DA. . American Journal of Pathology 2005, 166(3), 695-708.
    • Habens F, Srinivasan N, Oakley F, Mann DA, Ganesan A, Packham G. . Apoptosis 2005, 10(3), 481-491.
    • Mann DA, Oakley F. . Journal of Hepatology 2005, 42(4), 610-611.
    • Oakley F, Meso M, Iredale JP, Green K, Marek CJ, Zhou X, May MJ, Millward-Sadler H, Wright MC, Mann DA. . Gastroenterology 2005, 128(1), 108-120.
    • Smith PG, Oakley F, Fernandez M, Mann DA, Lemoine NR, Whitehouse A. . Gene Therapy 2005, 12(19), 1465-1476.
    • Mann J, Patrick CN, Cragg MS, Honeychurch J, Mann DA, Harris M. . Journal of Immunology 2005, 175(10), 6560-6569.
    • Bertrand-Philippe M, Ruddell RG, Arthur MJ, Thomas J, Mungalsingh N, Mann DA. . Journal of Biological Chemistry 2004, 279(23), 24530-24539.
    • Yeung IY, Phillips E, Mann DA, Barton CH. . Biochemical Society Transactions 2004, 32(6), 1008-1010.
    • Murphy F, Waung J, Collins J, Arthur MJ, Nagase H, Mann D, Benyon RC, Iredale JP. . Comparative Hepatology 2004, 3(s1), S8.
    • Takahra T, Smart DE, Oakley F, Mann DA. . International Journal of Biochemistry & Cell Biology 2004, 36(2), 353-363.
    • Monteleone G, Mann J, Monteleone I, Vavassori P, Bremner R, Fantini M, Vecchio GDelBlanco, Tersigni R, Alessandroni L, Mann D, Pallone F, MacDonald TT. . Journal of Biological Chemistry 2004, 279(6), 3925-32.
    • Oakley F, Trim N, Constandinou CM, Ye W, Gray AM, Frantz G, Hillan K, Kendall T, Benyon RC, Mann DA, Iredale JP. . The American Journal of Pathology 2003, 163(5), 1849-1858.
    • Bowen H, Lapham A, Phillips E, Yeung I, Alter-Koltunoff M, Levi BZ, Perry VH, Mann DA, Barton CH. . Journal of Biological Chemistry 2003, 278(38), 36017-36026.
    • Oakley F, Mann J, Ruddell RG, Pickford J, Weinmaster G, Mann DA. . Journal of Biological Chemistry 2003, 278(27), 24359-24370.
    • Mann DA, Smart DE. . Gut 2002, 50(6), 891-896.
    • Gao R, McCormick CJ, Arthur MJ, Ruddell R, Oakley F, Smart DE, Murphy FR, Harris MP, Mann DA. . Liver International 2002, 22(1), 15-22.
    • Bowen H, Biggs TE, Baker ST, Phillips E, Perry VH, Mann DA, Barton CH. . Transactions of the Biochemical Society 2002, 30(4), 774-777.
    • Bowen H, Biggs TE, Phillips E, Baker ST, Perry VH, Mann DA, Barton CH. . Journal of Biological Chemistry 2002, 277(38), 34997-5006.
    • Mann J, Oakley F, Johnson PW, Mann DA. . Journal of Biological Chemistry 2002, 277(19), 17125-17138.
    • Vincent KJ, Jones E, Arthur MJ, Smart DE, Trim J, Wright MC, Mann DA. . Gut 2001, 49(5), 713-719.
    • Smart DE, Vincent KJ, Arthur MJ, Eickelberg O, Castellazzi M, Mann J, Mann DA. . Journal of Biological Chemistry 2001, 276(26), 24414-24421.
    • Wright MC, Issa R, Smart DE, Trim N, Murray GI, Primrose JN, Arthur MJ, Iredale JP, Mann DA. . Gastroenterology 2001, 121(3), 685-698.
    • Trim JE, Samra SK, Arthur MJ, Wright MC, McAulay M, Beri R, Mann DA. . Journal of Biological Chemistry 2000, 275(9), 6657-63.
    • Lucchiari-Hartz M, van Endert PM, Lauvau G, Maier R, Meyerhans A, Mann D, Eichmann K, Niedermann G. . Journal of Experimental Medicine 2000, 191(2), 239-52.
    • Wilde GJ, Pringle AK, Sundstrom LE, Mann DA, Iannotti F. . European Journal of Neuroscience 2000, 12(11), 3863-3870.
    • Elsharkawy AM, Wright MC, Hay RT, Arthur MJ, Hughes T, Bahr MJ, Degitz K, Mann DA. . Hepatology 1999, 30(3), 761-769.
    • Biggs TE, Cooke SJ, Barton CH, Harris MP, Saksela K, Mann DA. . Journal of Molecular Biology 1999, 290(1), 21-35.
    • Renkema GH, Manninen A, Mann DA, Harris M, Saksela K. . Current Biology 1999, 9(23), 1407-1410.
    • Bahr MJ, Vincent KJ, Arthur MJ, Fowler AV, Smart DE, Wright MC, Clark IM, Benyon RC, Iredale JP, Mann DA. . Hepatology 1999, 29(3), 839-848.
    • Brana C, Biggs TE, Barton CH, Sundstrom LE, Mann DA. . Aids 1999, 13(12), 1443-1452.
    • Trowern AR, Mann DA. . Neuroscience Letters 1999, 272(1), 25-8.
    • T. Biggs,C. Barton,D. Mann. A proposed mechanism for the induction of activator protein 1 (AP-1) binding by HIV-1 negative factor(Nef) in the macrophage cell line RAW267.4 cells. Biochem Soc Trans 1998, 26(3), S263.
    • Clark IM, Rowan AD, Edwards DR, Bech-Hansen T, Mann DA, Bahr MJ, Cawston TE. . Biochemical Journal 1997, 324(2), 611-617.
    • S. J. Cooke,K. Coates,C. H. Barton,T. E. Biggs,S. J. Barrett,A. Cochrane,K. Oliver,J. A. McKeating,M. P. Harris,D. A. Mann. Regulated expression vectors demonstrate cell-type-specific sensitivity to human immunodeficiency virus type 1 Nef-induced cytostasis. J Gen Virol 1997, 78 ( Pt 2), 381-92.
    • K. Coates,S. J. Cooke,D. A. Mann,M. P. Harris. Protein kinase C-mediated phosphorylation of HIV-I nef in human cell lines. J Biol Chem 1997, 272(19), 12289-94.
    • K. Coates,V. Boulton,S. Cooke,D. Mann,M. Harris. Analysis of the interactions between Nef and cellular proteins. Res Virol 1997, 148(1), 68-70.
    • C. H. Barton,T. E. Biggs,T. R. Mee,D. A. Mann. The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line. J Gen Virol 1996, 77 ( Pt 8), 1643-7.
    • D. A. Mann,A. R. Trowern,F. L. Lavender,P. A. Whittaker,R. J. Thompson. Identification of evolutionary conserved regulatory sequences in the 5' untranscribed region of the neural-specific ubiquitin C-terminal hydrolase (PGP9.5) gene. J Neurochem 1996, 66(1), 35-46.
    • A. R. Trowern,R. Laight,N. MacLean,D. A. Mann. Detection of neuron-specific protein gene product (PGP) 9.5 in the rat and zebrafish using anti-human PGP9.5 antibodies. Neurosci Lett 1996, 210(1), 21-4.
    • D. A. Mann,I. Mikaelian,R. W. Zemmel,S. M. Green,A. D. Lowe,T. Kimura,M. Singh,P. J. Butler,M. J. Gait,J. Karn. A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression. J Mol Biol 1994, 241(2), 193-207.
    • U. Asseline,J. Grasby,F. Hamy,S. Iwai,D. A. Mann,C. Pritchard,J. Karn,M. J. Gait. HIV gene regulatory proteins tat and rev and their interactions with synthetic RNA. Nucleic Acids Symp Ser 1993, (29), 113-4.
    • S. Iwai,C. Pritchard,D. A. Mann,J. Karn,M. J. Gait. Recognition of the high affinity binding site in rev-response element RNA by the human immunodeficiency virus type-1 rev protein. Nucleic Acids Res 1992, 20(24), 6465-72.
    • P. Doherty,G. Rimon,D. A. Mann,F. S. Walsh. Alternative splicing of the cytoplasmic domain of neural cell adhesion molecule alters its ability to act as a substrate for neurite outgrowth. J Neurochem 1992, 58(6), 2338-41.
    • P. Doherty,L. H. Rowett,S. E. Moore,D. A. Mann,F. S. Walsh. Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs. Neuron 1991, 6(2), 247-58.
    • D. A. Mann,C. H. Barton,F. S. Walsh. Characterization of a regulatory region within the human neural cell adhesion molecule gene. Biochem Soc Trans 1990, 18(3), 410-2.
    • D. A. Mann,P. Doherty,F. S. Walsh. Increased intracellular cyclic AMP differentially modulates nerve growth factor induction of three neuronal recognition molecules involved in neurite outgrowth. J Neurochem 1989, 53(5), 1581-8.
    • P. Doherty,D. A. Mann,F. S. Walsh. Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures. J Cell Biol 1988, 107(1), 333-40.
    • P. Doherty,D. A. Mann,F. S. Walsh. Cholera toxin and dibutyryl cyclic AMP inhibit the expression of neurofilament protein induced by nerve growth factor in cultures of naive and primed PC12 cells. J Neurochem 1987, 49(6), 1676-87.
    • P. Doherty,D. A. Mann,F. S. Walsh. Cell-cell interactions modulate the responsiveness of PC12 cells to nerve growth factor. Development 1987, 101(3), 605-15.

  • Book Chapters

    • Mann J, Mann DA. . In: Signaling Pathways in Liver Diseases. Wiley Blackwell, 2015, pp.421-434.
    • Oakley F, Mann DA. . In: Stellate Cells in Health and Disease. Elsevier Inc, 2015, pp.251-270.

  • Conference Proceedings (inc. Abstracts)

    • Moir JAG, Mann D, Mann J, Charnley RM, Manas DM, French JJ, White SA. . In: Society of Academic and Research Surgery 2016 Annual Meeting. 2016, London: John Wiley & Sons Ltd.
    • Moir JAG, Mann D, Mann J, Charnley RM, Manas DM, French JJ, White SA. . In: Society of Academic and Research Surgery 2016 Annual Meeting. 2016, London: John Wiley & Sons Ltd.
    • Moles A, Butterworth J, Hunter JE, Sanchez AM, Tiniakos D, Mann D, Oakley F, Perkins ND. . In: 66th Annual Meeting of the American Association for the Study of Liver Diseases: The Liver Meeting 2015. 2015, San Francisco, California: John Wiley & Sons, Inc.
    • Locatelli L, Paoli PP, Hardy T, Howarth RM, Oakley F, Mann D. . In: The Liver Meeting 2015: 66th Annual Meeting of the American Association for the Study of Liver Diseases. 2015, San Francisco: John Wiley & Sons, Inc.
    • Luli S, Di Paolo D, Wilson C, Wright MC, Brown H, Ponzoni M, Mann D, Oakley F. . In: The Liver Meeting 2015: 66th Annual Meeting of the American Association for the Study of Liver Diseases. 2015, San Francisco: John Wiley & Sons, Inc.
    • Moles A, Butterworth J, Hunter J, Sanchez A, Mann D, Oakley F, Perkins ND. . In: 50th The International Liver Congress 2015. 2015, Vienna, Austria: Elsevier.
    • Moran-Salvador E, Paoli PP, Smith GR, Page A, Howarth RM, Oakley F, Mann J, Mann D. . In: The Liver Meeting 2015: 66th Annual Meeting of the American Association for the Study of Liver Diseases. 2015, San Francisco: John Wiley & Sons, Inc.
    • Hardy T, Sharkey V, Zeybel M, Mathers JC, French J, White S, Mann DA, Anstee QM, Mann J. . In: The International Liver Congress 2015 - 50th Annual meeting of the European Association for the Study of the Liver. 2015, Vienna, Austria: Elsevier BV.
    • Page A, Mann J, Mann D. . In: International Liver Congress 2015 - 50th Annual meeting of the European Association for the Study of the Liver. 2015, Vienna, Austria: Elsevier.
    • Robinson SM, Mann J, Manas DM, Mann DA, White SA. . In: Society of Academic and Research Surgery (SARS) Annual Meeting. 2014, Cambridge, UK: John Wiley & Sons, Inc.
    • Zeybel M, Hardy T, Fox C, Masson S, Mann D, Mathers J, Anstee Q, Mann J. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
    • Corbett L, Mann J, Mann DA. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
    • Luli S, Hill S, Wilson CL, Wright MC, Mann DA, Oakley F. . In: The International Liver Congress 2014: 49th Annual Meeting of the European Association for the Study of the Liver. 2014, London: Elsevier BV.
    • Corbett L, Mann J, Mann D. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier.
    • Patman GL, Televantou D, Whitehead A, Piguet AC, Dufour JF, Day CP, Burt AD, Mann DA, Reeves HL. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, The Netherlands: Elsevier.
    • Patman GL, Televantou D, Whitehead A, Day CP, Oakley F, Mann DA, Burt AD, Anstee QM, Reeves HL, FLIP Investigators FP7-2007-2013. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier BV.
    • Probert PME, Ebrahimkhani MR, Oakley F, Burt AD, Mann DA, Wright MC. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier BV.
    • Robinson S, Mann J, Manas D, Mann D, White S. . In: 17th AUGIS Annual Scientific Meeting. 2013, Â鶹´«Ã½ upon Tyne, UK: John Wiley & Sons Ltd.
    • Robinson SM, Mann J, Manas DM, Mann DA, White SA. . In: Annual Meeting of the Society of Academic and Research Surgery. 2013, London, UK: John Wiley & Sons Ltd.
    • Gackowska A, Mann D, Mann J. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier BV.
    • Bodi I, Troakes C, Maekawa S, Attems J, Esiri MM, Hortobagyi T, King A, Love S, Mann D, Neal JW, Al-Sarraj S. . In: Proceedings of the 114th Meeting of the British Neuropathological Society, Institute of Child Health. 2013, London: Wiley-Blackwell.
    • Moles A, Murphy L, Bagchi J, Mann J, Oakley F, Mann D. . In: 48th Annual meeting of the European Association for the Study of the Liver. 2013, Amsterdam, Netherlands: Elsevier BV.
    • Robinson SM, Mann JJ, Vasilaki A, Manas DM, Mann DA, White SA. . In: Annual Meeting of the Society of Academic and Research Surgery. 2013, London, UK: John Wiley & Sons Ltd.
    • Robinson SM, Mann J, Manas DM, Mann DA, White SA. . In: Gastrointestinal Cancers Symposium. 2013, San Francisco, CA, USA: American Society of Clinical Oncology.
    • Chakraborty JB, Wilson CL, Oakley F, Mann J, Mann DA. . In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
    • Green NJ, Suwara MI, Borthwick LA, Mann DA, Fisher AJ. . In: Winter Meeting of the British Thoracic Society. 2012, London: BMJ Group.
    • Suwara MI, Borthwick LA, Mahida R, Green NJ, Mayer-Barber K, Gardner A, Mann J, Wynn TA, Corris PA, Farrow SN, Mann DA, Fisher AJ. . In: Winter Meeting of the British Thoracic Society. 2012, London: BMJ Group.
    • Moles A, Mann DA, Oakley F. . In: 47th Annual Meeting of the European Association for the Study of the Liver (EASL). 2012, Barcelona, Spain: Elsevier BV.
    • Robinson S, Mann J, Manas D, Mann D, White S. . In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
    • Robinson SM, Mann J, Manas DM, Mann DA, White SA. . In: Annual Meeting of the Society of Academic and Research Surgery. 2012, Nottingham, UK: John Wiley & Sons Ltd.
    • Zeybel M, Walsh MJ, Chu DC, Tsukamoto H, Mann DA, Mann J. . In: 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). 2012, Boston, Massachusetts, USA: John Wiley & Sons, Inc.
    • Robinson SM, Mann J, Burt AD, Manas DM, Mann DA, White SA. . In: Annual Meeting of the Society of Academic and Research Surgery. 2012, Nottingham, UK: John Wiley & Sons Ltd.
    • Robinson S, Mann J, Manas D, Burt A, Mann D, White S. . In: Digestive Disorders Federation Meeting. 2012, Liverpool, UK: BMJ Group.
    • Wilson CL, Oakley F, Mann D. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Perugorria M, Oakley F, Mann J, Sharif O, Knapp S, Mann D. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Suwara MI, Mahiba R, Borthwick LA, Mann J, Corris PA, Farrow SN, Mann DA, Fisher A. . In: Journal of Heart and Lung Transplantation: 31st Annual Meeting and Scientific Sessions on International Society for Heart and Lung Transplantation. 2011, San Diego, California, USA: Elsevier Inc.
    • Oakley F, Murphy L, Wright M, Mann D. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Zeybel M, Oakley F, Burt AD, Mann DA, Mann J. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Robinson SM, Mann J, Burt AD, Manas DM, Mann DA, White SA. . In: British Journal of Surgery: Annual Meeting of the Society of Academic and Research Surgery. 2011, Dublin, Ireland: John Wiley & Sons Ltd.
    • Perugorria M, Wilson C, Zeybel M, Amin S, Oakley F, Tsukamoto H, Mann D, Mann J. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Tsukamoto H, Zhu NL, Asahina K, Mann DA, Mann J. . In: Hepatology Research: Single Topic Conference on NASH. 2011, Tokyo, Japan: Wiley-Blackwell Publishing Ltd.
    • Mahida RY, Suwara M, Johnson G, Mann D, Corris PA, Borthwick L, Fisher AJ. . In: Thorax: Winter Meeting of the British Thoracic Society. 2011, Westminster, UK: BMJ Group.
    • Moles A, Oakley F, Mann DA. . In: Journal of Hepatology: 46th Annual Meeting of the European Association for the Study of the Liver (EASL). 2011, Berlin, Germany: Elsevier BV.
    • Perugorria M, Oakley F, Mann J, Sharif O, Knapp S, Mann DA. . In: 61st Annual Meeting of the American Association for the Study of Liver Diseases. 2010, Boston, MA: Hepatology: Wiley-Blackwell.
    • Gardner A, Brodlie MJ, Mann DA, Borthwick LA, Fisher AJ. . In: Thorax: British Thoracic Society Winter Meeting. 2010, Westminster, UK: BMJ Group.
    • Yang M, Chiang YM, Wang C, Mann D, Mann J, Tsukamoto H. . In: 61st Annual Meeting of the American Association for the Study of Liver Diseases. 2010, Boston, MA: Hepatology: Wiley-Blackwell.
    • Chakraborty JB, Mann J, Oakley F, Burt AD, Mann DA. . In: 61st Annual Meeting of the American Association for the Study of Liver Diseases. 2010, Boston, MA: Hepatology: Wiley-Blackwell.
    • Suwara MI, Borthwick LA, Mann J, Fisher AJ, Mann DA. . In: Thorax: British Thoracic Society Winter Meeting. 2010, Westminster, UK: BMJ Group.
    • Mann J, Oakley F, Burt AD, Tsukamoto H, Mann D. . In: 61st Annual Meeting of the American Association for the Study of Liver Diseases. 2010, Boston, MA: Hepatology: Wiley-Blackwell.
    • Fearn A, Oakley F, Mann D, Sheerin NS. . In: North East Post-Graduate Conference. 2009, Â鶹´«Ã½ Upon Tyne, UK.
    • Fearn A, Oakley F, Mann D, Sheerin NS. . In: Renal Association Meeting (Joint with British Renal Society). 2009, Liverpool, UK.
    • Elsharkawy AM, Gieling RG, Oakley F, Kendall T, Burt AD, Mann DA. . In: 43rd Annual Meeting of the European Association for the Study of the Liver. 2008, Milan, Italy: Journal of Hepatology: Elsevier.
    • Mann DA, Mann J. . In: 2nd International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis. 2007, Kobe, Japan: Journal of Gastroenterology and Hepatology: Blackwell Publishing.
    • Clark IM, Bigg HF, Rowan AD, Edwards DR, Mann DA, Bahr MJ, Cawston TE. . In: Tissue Inhibitors of metalloproteinases in development and disease: proceedings of the Inhibitors of Metalloproteinases Conference. 2000, Banff, Canada: Harwood Academic Press.

  • Editorials

    • Robinson SM, Mann DA, Manas DM, Oakley F, Mann J, White SA. . British Journal of Cancer 2016, 115(8), e8-e8.
    • Borthwick LA, Mann DA. . Nature Reviews Gastroenterology & Hepatology 2016, 13(6), 320-322.
    • Zeybel M, Mann DA, Mann J. . Journal of Hepatology 2013, 59(6), 1349-1353.
    • Mann DA, Marra F. . Journal of Hepatology 2010, 52(6), 949-950.

  • Letters

    • Ellis EL, Mann DA. . Journal of Hepatology 2012, 57(6), 1392-1392.
    • Menon R, Baborie A, Jaros E, Mann D, Ray P, Larner A. . Journal of Neurology, Neurosurgery and Psychiatry 2010.

  • Notes

    • Malehmir M, Pfister D, Gallage S, Szydlowska M, Inverso D, Kotsiliti E, Leone V, Peiseler M, Surewaard BGJ, Rath D, Ali A, Wolf MJ, Drescher H, Healy ME, Dauch D, Kroy D, Krenkel O, Kohlhepp M, Engleitner T, Olkus A, Sijmonsma T, Volz J, Deppermann C, Stegner D, Helbling P, Nombela-Arrieta C, Rafiei A, Hinterleitner M, Rall M, Baku F, Borst O, Wilson CL, Leslie J, O'Connor T, Weston CJ, Chauhan A, Adams DH, Sheriff L, Teijeiro A, Prinz M, Bogeska R, Anstee N, Bongers MN, Notohamiprodjo M, Geisler T, Withers DJ, Ware J, Mann DA, Augustin HG, Vegiopoulos A, Milsom MD, Rose AJ, Lalor PF, Llovet JM, Pinyol R, Tacke F, Rad R, Matter M, Djouder N, Kubes P, Knolle PA, Unger K, Zender L, Nieswandt B, Gawaz M, Weber A, Heikenwalder M. . Nature Medicine 2022, 28, 600.
    • Ellis EL, Mann DA. . Journal of Hepatology 2014, 60(2), 468-469.

  • Reviews

    • Brennan PN, Elsharkawy AM, Kendall TJ, Loomba R, Mann DA, Fallowfield JA. . Nature Reviews Gastroenterology and Hepatology 2023, 20, 679–688.
    • Geh D, Leslie J, Rumney R, Reeves HL, Bird TG, Mann DA. . Nature Reviews Gastroenterology and Hepatology 2022.
    • Wilson CL, Mann DA, Borthwick LA. . Advanced Drug Delivery Reviews 2017, 121, 124-132.
    • Hardy T, Mann DA. . Gut 2016, 65(11), 1895-1905.
    • Dyson JK, Hirschfield GM, Adams DH, Beuers U, Mann DA, Lindor KD, Jones DEJ. . Nature Reviews Gastroenterology & Hepatology 2015, 12(3), 147-158.
    • Miousse IR, Currie R, Datta K, Ellinger-Ziegelbauer H, French JE, Harrill AH, Koturbash I, Lawton M, Mann D, Meehan RR, Moggs JG, O'Lone R, Rasoulpour RJ, Pera RAR, Thompson K. . Toxicology 2015, 335, 11-19.
    • Page A, Mann DA. . Clinics and Research in Hepatology and Gastroenterology 2015, 39(Suppl. 1), S64-S68.
    • Wallace MC, Friedman SL, Mann DA. . Seminars in Liver Disease 2015, 35(2), 107-118.
    • Mann DA. . Hepatology 2014, 60(4), 1418-1425.
    • Mann DA, Oakley F. . Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013, 1832(7), 905-910.
    • Mann J, Mann DA. . Current Opinion in Rheumatology 2013, 25(1), 101-107.
    • Ellis EL, Mann DA. . Journal of Hepatology 2012, 56(5), 1171-1180.
    • Robinson S, Manas DM, Pedley I, Mann D, White SA. . Surgical Oncology 2011, 20(2), 57-72.
    • Robinson SM, Mann DA. . Clinical Science 2010, 118(11-12), 691-705.
    • Ebrahimkhani MR, Elsharkawy AM, Mann DA. . Expert Reviews in Molecular Medicine 2008, 10, e11.
    • Ruddell RG, Mann DA, Ramm GA. . Journal of Hepatology 2008, 48(4), 666-675.
    • Axon A, Cowie DE, Mann DA, Wright MC. . Toxicology 2008, 246(1), 40-44.
    • Elsharkawy AM, Mann DA. . Hepatology 2007, 46(2), 590-597.
    • Arthur MJ, Iredale JP, Mann DA. . Alcoholism: Clinical and Experimental Research 1999, 23(5), 940-943.