麻豆传媒

Introduction

I am primarily interested in the cellular and molecular mechanisms that regulate the induction of the potent matrix-degrading proteinases that are involved in pathological tissue destruction. My focus is on both the metalloprteinases and the serine proteinases since these act extracellularly to degrade extacellular matrices.
My work therefore encompasses molecular events that occur both extracellulary (eg. proenzyme activation) as well as intracellularly (eg. cell signalling).
The generation of a detailed understanding of such fundamental events that drive the tissue destruction prevalent in arthritis may well yield new therapeutic targets to prevent further joint damage.

Background

I initially trained as a proteinase biologist gaining expertise in enzyme purification and characterisation. I also have experience in enzyme processing and more recently as a cell and molecular biologist.

Qualifications

BSc (Hons) in Biological Sciences (Plymouth, 1983).
PhD in Protein Biochemistry (Cambridge, 1989).

Previous Positions

Post-doctoral Researcher, Rheumatology Research Unit, Addenbrookes Hospital , Cambridge.
Post-doctoral Researcher, Animal Health Trust, Newmarket.
Post-doctoral Researcher, Joint Diseases Lab, Shriners Hospital, Montreal, Canada.
PhD Student, Strangeways Research Lab, Cambridge.

Research Interests

I am a proteinase biochemist with an interest in the molecular mechanisms that regulate enzymic activity and the transcriptional control of proteinase genes within the setting of joint diseases such as rheumatoid and osteoarthritis.

Other Expertise

Enzyme catalysis, structure/function and purification.
Inflammation cytokines and growth factors.
Signal transduction.

Current Work

Current projects focus on understanding the molecular effects that mediate synergistic gene transcription of various metalloproteinases as well as identify proteinases that are involved in the activation cascades of these extracellular matrix-degrading enzymes.
Other projects are assessing the impact of various signal transduction pathways that lead to the induction of metalloproteinase genes in chondrocytes.

Future Research

To delineate the interplay of multiple signal transduction pathways that mediate both transcriptional and post-transcriptional gene regulation of proteinases in connective tissue cells, and to further expand our understanding of the roles of key enzymes in cartilage destruction.

Research Roles

I am the Principal Investigator leading a team of researchers within the group that focus on the chondrocyte, the sole cell type present in articular cartilage. We are investigating the cell signalling that promotes the expression of matrix-degrading enzymes, and also study the roles of these enzymes in the destructive process.

Postgraduate Supervision

I currently supervise 4 PhD students.

Esteem Indicators

Deputy Head of the Musculoskeletal Research Group
visiting Scientist at the McMaster Centre for Gene Therapeutics in Canada (Oct-Dec 2006)

Funding

Major funding includes AR-UK Project Grants, an Oliver Bird Collaborative PhD Grant, and an AR-UK PhD Studentship Grant, plus local charity funding.

Patents

Rowan AD, Buttle DJ. Cysteine proteinases, production and use. U.K. Patent 1987, No. 87 24278.

Keywords

Signalling, chondrocyte, cytokine, metalloproteinase, collagenase, serine proteinase.

• Ciechomska M, Wilson CL, Floudas A, Hui W, Rowan AD, van Eden W, Robinson JH, Knight AM. . Immunology 2014, 141(1), 70-78.
• Radwan M, Gavriilidis C, Robinson JH, Davidson R, Clark IM, Rowan AD, Young DA. . Arthritis & Rheumatism 2013, 65(5), 1290-1301.
• Bui C, Barter MJ, Scott JL, Xu Y, Galler M, Reynard LN, Rowan AD, Young DA. . FASEB Journal 2012, 26(7), 3000-3011.
• Xu Y, Barter MJ, Swan DC, Rankin KS, Rowan AD, Santibanez-Koref M, Lo Ighlin J, Young DA. . In: World Congress on Osteoarthritis. 2012, Barcelona, Spain: Elsevier Ltd.
• Litherland GJ, Elias MS, Curtis H, Rowan AD. . In: Autumn Meeting of the British Society for Matrix Biology (BSMB). 2012, 麻豆传媒 upon Tyne, UK: Wiley-Blackwell Publishing Ltd.
• Macdonald CDM, Rowan AD, Europe-Finner N. . In: Autumn Meeting of the British Society for Matrix Biology (BSMB). 2012, 麻豆传媒 upon Tyne, UK: Wiley-Blackwell Publishing Ltd.
• Xu Y, Barter MJ, Swan DC, Rankin KS, Rowan AD, Santibanez-Koref M, Loughlin J, Young DA. . In: World Congress on Osteoarthritis. 2012, Barcelona, Spain: Elsevier Ltd.
• Xu Y, Barter MJ, Swan DC, Rankin KS, Rowan AD, Santibanez-Koref M, Loughlin J, Young DA. . Osteoarthritis and Cartilage 2012, 20(9), 1029-1038.
• Radwan MA, Gabrielides C, Rowan AD, Robinson JH, Cawston TE, Young DA. . In: Autumn Meeting of the British Society for Matrix Biology (BSMB). 2012, 麻豆传媒 upon Tyne, UK: Wiley-Blackwell Publishing Ltd.
• Hui W, Litherland GJ, Elias MS, Kitson GI, Cawston TE, Rowan AD, Young DA. . Annals of the Rheumatic Diseases 2012, 71(3), 455-462.
• Goff I, Rowan A, Bateman BJ, Foster HE. . Archives of Disease in Childhood 2012, 97(7), 644-646.
• Ciechomska M, Wilson C, Rowan A, Robinson JH, Knight AM. . In: Annals of the Rheumatic Diseases: 31st European Workshop for Rheumatology Research. 2011, Amsterdam, Netherlands: BMJ Group.
• Zheng J, Rowan AD, Lilic D. . In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
• Cawston TE, Lakey RL, Rowan AD. . In: Clark, IM, ed. Matrix Metalloproteinase Protocols. New York: Humana Press, 2010, pp.245-255.
• Hui W, Litherland GJ, Jefferson M, Barter MJ, Elias MS, Cawston TE, Rowan AD, Young DA. . Rheumatology 2010, 49(11), 2043-2053.
• Milner JM, Patel A, Davidson RK, Swingler TE, Desilets A, Young DA, Kelso EB, Donell ST, Cawston TE, Clark IM, Ferrell WR, Plevin R, Lockhart JC, Leduc R, Rowan AD. . Arthritis & Rheumatism 2010, 62(7), 1955-1966.
• Richards CD, Kerr C, Fritz DK, Rowan AD, Langdon CM. . In: Cytokine: 8th Joint Conference of the International Cytokine Society. 2010, Chicago, Illinois, USA: Academic Press.
• Litherland GJ, Elias MS, Hui W, Macdonald CD, Catterall JB, Barter MJ, Farren MJ, Jefferson M, Rowan AD. . Journal of Biological Chemistry 2010, 285(29), 22414-22425.
• Lakey RL, Morgan TG, Rowan AD, Isaacs JD, Cawston TE, Hilkens CM. . Rheumatology 2009, 48(5), 502-7.
• Hui W, Young DA, Rowan AD, Cawston T. . In: International Journal of Experimental Pathology: Annual General Meeting of the British Society for Matrix Biology. 2009, York, UK: Wiley-Blackwell Publishing Ltd.
• Richards CD, Kerr C, Fritz DK, Rowan AD, Langdon CM. . In: Cytokine: 7th Joint Conference of the International Cytokine Society and the International Society for Interferon and Cytokine Research. 2008, Montreal, Cananda: Academic Press.
• Zhang Q, Hui W, Litherland GJ, Barter MJ, Davidson R, Darrah C, Donell ST, Clark IM, Cawston TE, Robinson JH, Rowan AD, Young DA. . Annals of the Rheumatic Diseases 2008, 67(11), 1633-41.
• Milner JM, Patel A, Rowan AD. . Arthritis & Rheumatism 2008, 58(12), 3644-3656.
• Rowan AD, Litherland GJ, Hui W, Milner JM. . Expert Opinion on Therapeutic Targets 2008, 12(1), 1-18.
• Farren M, Jefferson M, Rowan A. . In: Autumn Meeting of the British Society for Matrix Biology. 2008, Keele University: International Journal of Experimental Pathology, Wiley-Blackwell Publishing Ltd.
• Litherland GJ, Dixon C, Lakey RL, Robson T, Jones D, Young DA, Cawston TE, Rowan AD. . Journal of Biological Chemistry 2008, 283(21), 14221-14229.
• Bigg HF, Rowan AD, Barker MD, Cawston TE. . The FEBS Journal 2007, 274(5), 1246-1255.
• Rowan AD, Young DA. . Frontiers in Bioscience 2007, 12(2), 536-550.
• Peake NJ, Foster HE, Khawaja K, Cawston TE, Rowan AD. . Annals of the Rheumatic Diseases 2006, 65(4), 501-507.
• Catterall JB, Rowan AD, Sarsfield S, Saklatvala J, Wait R, Cawston TE. . Rheumatology 2006, 45(9), 1101-1109.
• Milner JM, Kevorkian L, Jones D, Young D, Wait R, Cravatt B, Clark IM, Rowan AD, Cawston TE. . Arthritis Research & Therapy 2006, 8(1), R23-30.
• Milner JM, Kevorkian L, Young DA, Jones D, Wait R, Donell ST, Barksby HE, Patterson AM, Middleton JM, Cravatt BF, Clark IM, Rowan AD, Cawston TE. . Arthritis Research & Therapy 2006, 8(1), R23.
• Milner JM, Kevorkian L, Young DA, Jones D, Wait R, Cravatt B, Donell ST, Clark IM, Rowan AD, Cawston TE. . In: International Journal of Experimental Pathology: Autumn Meeting of the British Society for Matrix Biology. 2006, Manchester, UK: Wiley-Blackwell Publishing Ltd.
• Morgan TG, Rowan AD, Dickinson SC, Jones D, Hollander AP, Deehan D, Cawston TE. . Annals of the Rheumatic Diseases 2006, 65(2), 184-190.
• Barksby HE, Hui W, Wappler I, Peters HH, Milner JM, Richards CD, Cawston TE, Rowan AD. . Arthritis & Rheumatism 2006, 54(2), 540-550.
• Peake NJ, Khawaja K, Myers A, Nowell MA, Jones SA, Rowan AD, Cawston TE, Foster HE. . Rheumatology 2006, 45(12), 1485-1489.
• Barksby HE, Milner JM, Patterson AM, Peake NJ, Hui W, Robson T, Lakey R, Middleton J, Cawston TE, Richards CD, Rowan AD. . Arthritis & Rheumatism 2006, 54(10), 3244-3253.
• Milner JM, Rowan AD, Cawston TE, Young DA. . Arthritis Research & Therapy 2006, 8(5), R142.
• Shingleton WD, Jones D, Xu X, Cawston TE, Rowan AD. . Rheumatology 2006, 45(8), 958-965.
• Bigg HF, Wait R, Rowan AD, Cawston TE. . Journal of Biological Chemistry 2006, 281(30), 21082-21095.
• Peake NJ, Khawaja K, Myers A, Jones D, Cawston TE, Rowan AD, Foster HE. . Rheumatology 2005, 44(11), 1383-1389.
• Hui W, Barksby HE, Young DA, Cawston TE, McKie N, Rowan AD. . Annals of the Rheumatic Diseases 2005, 64(11), 1624-1632.
• Hui W, Cawston TE, Richards CD, Rowan AD. . Arthritis Research & Therapy 2004, 7(1), R57-R64.
• Rowan AD, Hui W, Cawston TE, Richards CD. . The American Journal of Pathology 2003, 162(6), 1975-1984.
• Cawston TE, Milner JM, Catterall JB, Rowan AD. . Biochemical Society Symposium 2003, 70, 125-133.
• Cawston TE, Milner JM, Catterall JB, Rowan AD. . In: Biochemical Society Symposia: Proteases and the Regulation of Biological Processes. 2003, London, UK: Portland Press.
• Milner JM, Rowan AD, Elliott SF, Cawston TE. . Arthritis & Rheumatism 2003, 48(4), 1057-1066.
• Hui W, Rowan AD, Richards CD, Cawston TE. . Arthritis & Rheumatism 2003, 48(12), 3404-3418.
• Cawston T, Wang H, Richards C, Rowan A. . In: Arthritis Research & Therapy: 3rd World Congress of the Global Arthritis Research Network (GARN). 2003, Miyakazi, Japan: BioMed Central Ltd.
• Hall M-C, Young DA, Waters JG, Rowan AD, Chantry A, Edwards DR, Clark IM. . Journal of Biological Chemistry 2003, 278(12), 10304-10313.
• Hui W, Cawston TE, Rowan AD. . Annals of the Rheumatic Diseases 2003, 62(2), 172-174.
• Vaidya B, Pearce SHS, Charlton S, Marshall N, Rowan AD, Griffiths ID, Kendall-Taylor P, Cawston TE, Young-Min S. . Rheumatology 2002, 41(2), 180-183.
• Vaidya B, Pearce SHS, Charlton S, Marshall N, Rowan AD, Griffiths ID, Kendall-Taylor P, Cawston TE, Young Min S. . Rheumatology 2002, 41(2), 180-183.
• Forrest IA, Ward C, Pritchard G, Rowan AD, Cawston TE, Corris PA. . In: Thorax: Winter Meeting of the British Thoracic Society. 2002, London: BMJ Group.
• Hall MC, Young DA, Rowan AD, Edwards DR, Clark IM. . BioTechniques 2002, 33(5), 1004-+.
• Koshy PJ, Henderson N, Logan C, Life PF, Cawston TE, Rowan AD. . Annals of the Rheumatic Diseases 2002, 61(8), 704-713.
• Koshy PJT, Lundy CJ, Rowan AD, Porter S, Edwards DR, Hogan A, Clark IM, Cawston TE. . Arthritis & Rheumatism 2002, 46(4), 961-967.
• Cawston TE, Koshy PJT, Rowan AD. . Methods in Molecular Biology 2001, 151, 389-398.
• Rowan AD. Cartilage catabolism in arthritis; factors that influence homeostasis. Expert Reviews Molecular Medicine 2001, 5 July, http://www-ermm.cbcu.cam.ac.uk / 01003209h.htm.
• Young-Min S, Pearce SHS, Charlton S, Marshall N, Rowan AD, Griffiths ID, Kendall-Taylor P, Cawston TE, Vaidya B. Cytotoxic T lymphocyte antigen-4 (CTLA-4) exon 1 polymorphism in early rheumatoid arthritis. In: RHEUMATOLOGY. 2001, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND: OXFORD UNIV PRESS.
• Hui W, Rowan A, Cawston T. . Annals of the Rheumatic Diseases 2001, 60(3), 254-261.
• Hui W, Rowan AD, Cawston TE. . Annals Rheumatic Diseases 2001, 60(3), 254-261.
• Cleaver CS, Rowan AD, Cawston TE. . Annals of the Rheumatic Diseases 2001, 60(2), 150-157.
• Cleaver C, Rowan AD, Cawston TE. . Annals Rheumatic Diseases 2001, 60(2), 150-157.
• Cawston TE, Carrere S, Catterall J, Duggleby R, Elliott S, Shingleton WD, Rowan AD. . In: Chadwick, D., Goode, J.A, ed. Chronic Obstructive Pulmonary Disease: Pathogenesis to Treatment. Chichester: Wiley, 2001, pp.205-228.
• Cawston TE, Carrere SL, Catterall JB, Duggleby RC, Elliott SC, Shingleton B, Rowan AD. . In: Novartis Foundation Symposium 234: Chronic Obstructive Pulmonary Disease: Pathogenesis to Treatment. 2001, Novartis Foundation, London: Chichester: Wiley.
• Cawston T, Carrere S, Catterall J, Duggleby R, Elliott S, Shingleton B, Rowan A. . In: Symposium on Chronic Obstructive Pulmonary Disease: Pathogenesis to Treatment. 2001, London, UK: Wiley-Blackwell.
• Hui W, Rowan AD, Cawston TE. . Cytokine 2001, 16(1), 31-35.
• Hui W, Rowan AD, Cawston T. . In: British Society for Rheumatology XVIII Annual General Meeting and the British Health Professionals in Rheumatology Spring Meeting. 2001, Rheumatology: Oxford University Press.
• Hui W, Rowan AD, Cawston TE. . Arthritis & Rheumatism 2001, 44(Supplement 9), S62 no. 57.
• Rowan AD, Koshy PJT, Shingleton WD, Degnan BA, Heath JK, Vernallis AB, Spaull JR, Life PF, Hudson K, Cawston TE. . Arthritis & Rheumatism 2001, 44(7), 1620-1632.
• Catterall JB, Carrere S, Koshy PJT, Degnan BA, Shingleton WD, Brinckerhoff CE, Rutter J, Cawston TE, Rowan AD. . Arthritis & Rheumatism 2001, 44(10), 2296-2310.
• Richards CD, Catterall JB, Cawston TE, Rowan AD. . Arthritis & Rheumatism 2001, 44(supplement), S112.
• Bigg HF, Rowan AD. . Current Opinion in Pharmacology 2001, 1(3), 314-320.
• Rowan AD, Billington CJ, Knight CG, Cawston TE. . In: Conference on Tissue Inhibitors of Metalloproteinases in Development and Disease. 2000, Banff, Canada: Harwood Academic Publishers, Gmbh.
• Rowan AD, Billington CJ, Knight CG, Cawston TE. . In: Tissue inhibitors of metalloproteinases in development and diseases: proceedings of the Inhibitors of Metalloproteinases Conference. 2000, Banff, Canada: Harwood Academic.
• Clark IM, Rowan AD, Cawston TE. Matrix metalloproteinases inhibitors in the treatment of arthritis. Current Opinions in Anti-inflammatory and Immunomodulatory Investigative Drugs 2000, 2, 16-25.
• Clark IM, Bigg HF, Rowan AD, Edwards DR, Mann DA, Bahr MJ, Cawston TE. . In: Tissue Inhibitors of metalloproteinases in development and disease: proceedings of the Inhibitors of Metalloproteinases Conference. 2000, Banff, Canada: Harwood Academic Press.
• Shingleton WD, Ellis AJ, Rowan AD, Cawston TE. . Journal of Cellular Biochemistry 2000, 79(4), 519-531.
• Shingleton WD, Ellis AJ, Rowan AD, Cawston TE. . Journal of Cellular Biochemistry 2000, 79(4), 519-531.
• Hui W, Rowan AD, Cawston TE. . Cytokine 2000, 12(6), 765-769.
• Koshy PJT, Rowan AD, Life PF, Cawston TE. . Analytical Biochemistry 1999, 275(2), 202-207.
• Rowan A, Bataille V, MacKie R, Healy E, Bicknell D, Bodmer W, Tomlinson I. . Journal of Investigative Dermatology 1999, 112(4), 509-511.
• Cawston T, Billington C, Cleaver C, Elliott S, Hui W, Koshy P, Shingleton B, Rowan A. . Annals of the New York Academy of Sciences 1999, 878, 120-129.
• Cawston T, Billington C, Cleaver C, Elliott S, Hui W, Koshy P, Shingleton B, Rowan A. . In: Inhibition of Matrix Metalloproteinases Therapeutic Applications. 1999, Tampa, Florida: Wiley-Blackwell Publishing, Inc.
• Cawston T, Billington C, Cleaver C, Elliott S, Hui W, Koshy P, Shingleton B, Rowan A. . In: Inhibition of Matrix Metalloproteinases: Therapeutic Applications. 1999, Tampa, Florida, USA: New York Academy of Sciences.
• Hodges, D.J., Reid, D.G., ROWAN, A.D., Clark, I.M., Cawston, T.E. Preparation of recombinant tissue inhibitor of metalloproteinases-1 (TIMP-1) in high yield and identification of a hydrophobic surface feature. European Journal Biochemistry 1998, 257, 562-569.
• Cawston TE, Rowan AD. . British Journal of Rheumatology 1998, 37(4), 353-356.
• Cawston TE, Curry VA, Summers CA, Clark IM, Riley GP, Life PF, Spaull JR, Goldring MB, Koshy PJT, Rowan AD, Shingleton WD. . Arthritis & Rheumatism 1998, 41(10), 1760-1771.
• Clark IM, Rowan AD, Edwards DR, Bech-Hansen T, Mann DA, Bahr MJ, Cawston TE. . Biochemical Journal 1997, 324(2), 611-617.
• Macdonald CD, Falconer AMD, Chan CM, Wilkinson DJ, Skelton A, Reynard L, Litherland GJ, Europe-Finner GN, Rowan AD. . PLoS ONE 2018, 13(11), e0207240.
• Baker J, Falconer AMD, Wilkinson DJ, Europe-Finner GN, Litherland GJ, Rowan AD. . PLoS ONE 2018, 13(4), e0195864.
• Wilkinson DJ, Arques MdC, Huesa C, Rowan AD. . British Journal of Pharmacology 2018, 176(1), 38-51.
• Chan CM, MacDonald CD, Litherland GJ, Wilkinson DJ, Skelton A, Europe-Finner GN, Rowan AD. . The Journal of Biological Chemistry 2017, 292(5), 1625-1636.
• Wilkinson DJ, Habgood A, Lamb HK, Thompson P, Hawkins AR, Desilets A, Leduc R, Steinmetzer T, Hammami M, Lee MS, Craik CS, Watson S, Lin H, Milner JM, Rowan AD. . Arthritis and Rheumatology 2017, 69(8), 1601–1611.
• Wilkinson DJ, Desilets A, Lin H, Charlton S, Del Carmen Arques M, Falconer A, Bullock C, Hsu Y-C, Birchall K, Hawkins A, Thompson P, Ferrell WR, Lockhart J, Plevin R, Zhang Y, Blain E, Lin S-W, Leduc R, Milner JM, Rowan AD. . Scientific Reports 2017, 7(1), 16693.
• Williams RC, Skelton AJ, Todryk SM, Rowan AD, Preshaw PM, Taylor JJ. . PLOS One 2016, 11(2), e0148024.
• Huesa C, Ortiz AC, Dunning L, McGavin L, Bennett L, McIntosh K, Crilly A, Kurowska-Stolarska M, Plevin R, van't Hof RJ, Rowan AD, McInnes IB, Goodyear CS, Lockhart JC, Ferrell WR. . Annals of Rheumatic Diseases 2016, 75(11), 1989-1997.
• Zheng J, vandeVeerdonk FL, Crossland KL, Smeekens SP, Chan CM, AlShehri T, Abinun M, Gennery AR, Mann J, Lendrem DW, Netea MG, Rowan AD, Lilic D. . European Journal of Immunology 2015, 45(10), 2834-2846.
• Tsompani D, Barter MJ, Rowan AD, Young DA. . In: Joint meeting of British Societies for Matric Biology and Developmental Biology 'The musculoskeltetal system; from development to disease'. 2015, University of East Anglia, Norwich, UK: Wiley-Blackwell.
• Rowan AD, Litherland GJ. . Biochemical Society Transactions 2015, 43(5), 1051-1056.
• Proctor CJ, Macdonald C, Milner JM, Rowan AD, Cawston TE. . Arthritis & Rheumatology 2014, 66(4), 979-989.
• Rowan A, Wyllie RA, Foster HE. . Medicine 2014, 42(5), 243-250.
• Litherland GJ, Hui W, Elias MS, Wilkinson DJ, Watson S, Huesa C, Young DA, Rowan AD. . Arthritis & Rheumatology 2014, 66(8), 2175-2187.
• Hui W, Young DA, Rowan AD, Xu X, Cawston TE, Proctor CJ. . Annals of the Rheumatic Diseases 2014, 1-10.
• Radwan M, Wilkinson DJ, Hui W, Destrument AP, Charlton SH, Barter MJ, Gibson B, Coulombe J, Gray DA, Rowan AD, Young DA. . Annals of the Rheumatic Diseases 2014.
• Cawston TE, Young DA, Rowan DD. . In: Hochberg MC; Silman AJ; Smolen JS; Weinblatt ME; Weisman MH, ed. Rheumatology: Sixth Edition. Philadelphia, PA: Elsevier Inc, 2014, pp.152-159.
• Culley KL, Hui W, Barter MJ, Davidson RK, Swingler TE, Destrument APM, Scott JL, Donell ST, Fenwick S, Rowan AD, Young DA, Clark IM. . Arthritis & Rheumatism 2013, 65(7), 1822-1830.
• Murray MY, Birkland TP, Howe JD, Rowan AD, Fidock M, Parks WC, Gavrilovic J. . PLoS ONE 2013, 8(5), e63555.
• Baker J, Litherland GJ, Rowan AD. . In: Rheumatology 2013. 2013, Birmingham, UK: Oxford University Press.
• Falconer AMD, Chan CM, Gray J, Nagashima I, Holland RA, Shimizu H, Pickford AR, Rowan AD, Wilkinson DJ. . Journal of Biological Chemistry 2019, 294(26), 10266-10277.
• Al Shehri T, Gilmour K, Gothe F, Loughlin S, Bibi S, Rowan AD, Grainger A, Mohanadas T, Cant AJ, Slatter MA, Hambleton S, Lilic D, Leahy TR. . Journal of Clinical Immunology 2019, 39, 776-785.
• Hodgson D, Rowan AD, Falciani F, Proctor CJ. . PLoS computational biology 2019, 15(1), e1006685.