麻豆传媒

Current Post

Senior Lecturer

Internal Responsibilities

Faculty of Medical Sciences MRes Programmes Degree Programme Director

Chair Stage 2 Biomedical Sciences Board of Examiners

Faculty of Medical Science Postgraduate Research Committee

Faculty of Medical Sciences International Recruitment Committee

External Responsibilities

Current:

External Examiner, University of Edinburgh BSc Cell Biology and Molecular Biology (2024-28)

External examiner, University of East Anglia MRes Clinical Science (2024-27)

Previous:

2020-24          External examiner, University of Aberdeen BSc Microbiology, Biotechnology and

Genetics

2017- 21         External examiner, University of Leeds BSc and MBiol BSc Medical Sciences

2017- 21         External examiner, Coventry University MSc Molecular Biology

2013-17          External examiner, Glasgow University Molecular and Cellular Biology BSc (Hons)

2010-14 BBSRC Committee C Core Panel Member

2007-13 Member, Biochemical Society Theme Panel 1 (Deputy Chair 2009-2013)

Qualifications

1992 PhD on pre-mRNA splicing with Prof. Jean Beggs (University of Edinburgh)

1988 BSc in Biochemistry (Imperial College London)

Previous Positions

2001-2007 MRC Senior Non-clinical Research Fellow (麻豆传媒)

1996 - 2001 Research Group Leader and Wellcome Trust Research Career Development Fellow (Institute of Cell and Molecular Biology, University of Edinburgh).

1992 - 1996 Postdoctoral research with Prof. Peter Walter (University of California School of Medicine, San Francisco USA), studying protein targeting to the secretory pathway. During this time I held independent Fellowships from the American Cancer Society and European Molecular Biology Organisation

Memberships

Biochemical Society, Association of University Teachers

Awards

2001-2007 Medical Research Council Senior Non-Clinical Research Fellowship

1996-2000 Wellcome Trust Research Career Development Award

1995-1996 American Cancer Society (California Division) Senior Postdoctoral Fellowship

1992-1994 European Molecular Biology Organisation Long Term Fellowship

1988-1992 Wellcome Trust Prize Studentship and Prize Postdoctoral Fellowship

Faculty of Medical Sciences MRes Programmes Degree Programme Director

Chair Stage 2 Biomedical Sciences Board of Examiners

Module leader: BGM1004 (Genetics), BGM2061 (Protein Trafficking and Biological Membranes), BGM2063 (Approaches to Analysis of Genes and Genomes).

Contributor: CMB1011 (Professional and Practical Skills for Bioscientists), CMB2001 (Control of Eukaryotic Gene Expression), BGM2062 (Advanced Protein Analysis), and BGM3063 (Biochemistry of Gene Expression).

Research Interests

Specific: Ribonucleoprotein biogenesis and function, with focus on the ribosome and signal recognition particle.

General: Targeting, translocation and sorting events within the cell. Organelle function and biogenesis. Cell biology of ribonucleoprotein particles.

Funding

2002 Wellcome Trust vacation scholarship £1,160
2001-2006 Medical Research Council Senior Non-Clinical Research Fellowship £894,420
2004-2006 BBSRC Project Grant £398,873
2006-2009 BBSRC Project Grant £319,023
2007-2009 BBSRC Project Grant £476,723 (fEC cost)

• Articles

  • Cao M, Day AM, Galler M, Latimer HR, Byrne DP, Foy TW, Dwyer E, Bennett E, Palmer J, Morgan BA, Eyers PA, Veal EA. . Molecular Cell 2023, 83(17), 3140-3154.e7.
  • McQuade R, Kometa S, Brown J, Bevitt D, Hall J. . Assessment and Evaluation in Higher Education 2020, 45(8), 1181-1191.
  • Leung E, Schneider C, Yan F, Mohi-El-Din H, Kudla G, Tuck A, Wlotzka W, Doronina VA, Bartley R, Watkins NJ, Tollervey D, Brown JD. . Nucleic Acids Research 2014, 42(16), 10698-10710.
  • Odon V, Luke GA, Roulston C, de Felipe P, Ruan L, Escuin-Ordinas H, Brown JD, Ryan MD, Sukhodub A. . Molecular Biology and Evolution 2013, 30(8), 1955-1965.
  • Brown JD, Day AM, Taylor SR, Tomalin LE, Morgan BA, Veal EA. . Cell Reports 2013, 5(5), 1425-1435.
  • Sharma P, Yan F, Doronina VA, Escuin-Ordinas H, Ryan MD, Brown JD. . Nucleic Acids Research 2012, 40(7), 3143-3151.
  • Yan F, Doronina VA, Sharma P, Brown JD. . Biochemical Society Transactions 2010, 38, 1576-1580.
  • de Felipe P, Luke GA, Brown JD, Ryan MD. . Biotechnology Journal 2010, 5(2), 213-223.
  • Leung E, Brown JD. . Biochemical Society Transactions 2010, 38, 1093-1098.
  • Schneider C, Leung E, Brown J, Tollervey D. . Nucleic Acids Research 2009, 37(4), 1127-1140.
  • Doronina VA, Wu C, de Felipe P, Sachs MS, Ryan MD, Brown JD. . Molecular and Cellular Biology 2008, 28(13), 4227-4239.
  • van Nues RW, Leung E, McDonald J, Dantuluru I, Brown JD. . RNA Biology 2008, 5(2), 73-83.
  • Doronina VA, de Felipe P, Wu C, Sharma P, Sachs MS, Ryan MD, Brown JD. . Biochemical Society Transactions 2008, 36(4), 712-716.
  • van Nues RW, Brown JD. . Journal of Molecular Biology 2007, 368(3), 677-690.
  • Ng W, Sergeyenko T, Zeng N, Brown JD, Römisch K. . Journal of Cell Science 2007, 120(4), 682-691.
  • Zwieb C, van Nues RW, Rosenblad MA, Brown JD, Samuelsson T. . RNA 2005, 11(1), 7-13.
  • van Nues RW, Brown JD. . RNA 2004, 10(1), 75-89.
  • Blackwell C, Russell CL, Argimon S, Brown AJP, Brown JD. . Yeast 2003, 20(15), 1235-1241.
  • de Felipe P, Hughes LE, Ryan MD, Brown JD. . The Journal of Biological Chemistry 2003, 278(13), 11441-11448.
  • Brown JD. . Current Biology 2001, 11(17), R710-712.
  • Robb A, Brown JD. . Molecular Cell 2001, 8(3), 484-486.
  • Ciufo LF, Brown JD. . Current Biology 2000, 10(20), 1256-1264.
  • Mason N, Ciufo LF, Brown JD. . The EMBO Journal 2000, 19, 4164-4174.

• Book Chapters

  • Brown JD, Ryan MD. . In: Atkins, JF; Gesteland, RF, ed. Recoding: Expansion of Decoding Rules Enriches Gene Expression. Berlin: Springer, 2010, pp.101-121.
  • Blackwell C, Brown J. . In: Ronald L. Cihlar and Richard A. Calderon, ed. Candida albicans: Methods and protocols. New York: Humana Press, 2009, pp.133-148.

• Review

  • Doronina VA, Brown JD. . Molecular Biology 2006, 40(4), 654-663.