麻豆传媒

Introduction

I am a Principal Investigator in the Congenital Heart Disease Group which sits in the Reproduction, Development and Child Health Theme. My work is on outcomes in adult congenital heart disease, in particular understanding the markers of decompensation and what matters to patients.

Background

Guildford High School, Guildford 1987- 1994

St George’s Hospital Medical School, London 1994-1999

• MBBS distinction Medicine
• Anatomy prize
• Brackenbury prize for Medicine

Adult Medical Training, Plymouth and London 1999-2003

• DHMSA (Diploma in History of Medicine Society of Apothecaries) 2000
• MRCP (UK) 2002

Great Ormond Street Hospital and Institute of Child Health 2003-2006

• British Heart Foundation Junior Fellowship
• (PhD) University College London

Adult Cardiology Training, Northern Deanery 2007-2016

• NIHR Academic Clinical Lecturer
• Academy of Medical Sciences Start-Up Grant
• British Society of Echocardiography Transthoracic Accreditation

Completion of Clinical Training 2016

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Orcid number:  

Memberships 

• Royal College of Physicians of Edinburgh
• British Cardiac Society
• British Congenital Cardiac Society
• ESC Grown up Congenital Heart Disease Working Group

Research Interests

How can we promote resilience in adults with congenital heart disease? 

Adults with congenital heart disease are a growing and increasingly complex patient group at risk of premature decompensation. As part of a collaborative research effort with Bill Chaudhry and Deborah Henderson I am interested in understanding both their medical and psychosocial issues that influence their general wellbeing. There are three ongoing strands to this work:

• Finding biomarkers that will indicate problems before they become clinically apparent
• Investigating the potential of microvascular function as an early marker of decompensation
• Understanding the psychosocial needs of this patient group

What is the role of transplant and mechanical assist for adults with congenital heart disease? 

The growing burden of heart failure in ACHD is reflected in the rapidly increasing numbers of referrals for transplant assessment to our centre. Donor organs are a scarce commodity and mechanical assist devices are not yet developed that can adequately support the complex failing single ventricle patient. Together with clinical colleagues, Katrijn Jansen, David Crossland, John O’Sullivan and Asif Hasan I am interested in understanding the current and future role of mechanical assist and heart transplant in the decompensating adult congenital patient.

What is the relationship between flow and morphology in adults with congenital heart disease? 

Surgical modification has been the main modifier of the natural history of congenital heart disease over recent decades. In the normal heart, recent work (link PFO paper) in collaboration with Kieren Hollingsworth has highlighted the potential relationship between subtle differences in cardiac morphology, flow and late pathophysiological complications in the setting of patent foramen ovale. I am interested in how this concept may be applied to more complex conditions, such as the Fontan palliation, to understand better where and how intervention might be designed and targeted to improve outcomes.

Technical expertise

Imaging (Tissue Doppler and 4D Flow MRI)

Patient Related Research

Teaching

I am lead for training in Adult Congenital Heart Disease (ACHD) in the Northern Deanery and sit on the Speciality Trainee Committee. I contribute to Regional and National clinical teaching programmes in Adult Congenital Heart Disease. I currently provide supervision to undergraduate and master’s students from our own medical school and others across the UK.

Administration

Northern Deanery

Co-ordinator for trainee attachments in Adult Congenital Heart Disease

North East and North Cumbria Congenital Heart Disease Operational Delivery Network

ACHD Lead

Congenital Heart Disease Research Group

Administrative Lead

Clinical

Co-ordinator of Fontan MDT

• Lopes BS, Coats L, Anderson RH. Commentary: Shunting Between the Left Ventricle and Right Atrium Can Be Produced by Straddling Tricuspid Valve With Dual Orifices. Semin Thorac Cardiovasc Surg 2020, 32(1), 143-144. In Preparation.
• Dewhurst P, Coats L, Parikh JD, Hollingsworth KG, Gan L. The role of flow rotation in the adult right atrium: a 4D flow cardiovascular magnetic resonance study. Physiol Meas 2020, 41(3), 035007. In Preparation.
• Vittery E, O'Sullivan J, Polyviou S, Coats L, Chaudhry B. . Pediatric Cardiology 2019, 40, 1101-1102.
• Crossland DS, Jansen K, Parry G, Harper A, Perri G, Davidson A, De Rita F, Hermuzi A, Nassar M, Seller N, MacGowan GA, Hasan A, O'Sullivan JJ, Coats L. . Heart 2019, 105(2), 1741-1747.
• Rico-Armada A, Crossland DS, Coats L, Reinhardt Z, Hermuzi A, Seller N, Hasan A, O'Sullivan JJ. . Cardiology in the Young 2019, 29(7), 888-892.
• Agarwal R, Chaudhry B, Jansen K, O'Sullivan J, Hudson J, Allen J, Coats L. . Physiological Measurement 2019, 40(6), 06NT01.
• Hutchinson S, Crossland DS, Chaudhry B, Coats L. . Cardiology in the Young 2018, 28(10), 1099-1104.
• Polyviou S, O'Sullivan J, Hasan A, Coats L. . The American Journal of Cardiology 2018, 122(1), 182-183.
• Cauldwell M, Steer PJ, Bonner S, Asghar O, Swan L, Hodson K, Head CEG, Jakes AD, Walker N, Simpson M, Bolger AP, Siddiqui F, English KM, Maudlin L, Abraham D, Sands AJ, Mohan AR, Curtis SL, Coats L, Johnson MR. . Heart 2018, 104(5), 401-406.
• Kenny LA, DeRita F, Nassar M, Dark J, Coats L, Hasan A. . Annals of Cardiothoracic Surgery 2018, 7(1), 152-159.
• Parikh JD, Kakarla J, Keavney B, O'Sullivan JJ, Ford GA, Blamire AM, Hollingsworth KG, Coats L. . PLoS One 2017, 12(3), e0173046.
• Duong P, Coats L, O'Sullivan J, Crossland D, Haugk B, Babu-Narayan SV, Keegan J, Hudson M, Parry G, Manas D, Hasan A. . ESC Heart Failure 2017, 4(4), 675–678.
• Haugk B, Bury Y, Coats L, O'Sullivan J, Hudson M. . Human Pathology 2017, 69, 140-140.
• Coats L, Crossland D, Hudson M, O'Sullivan J, Hasan A. . Heart 2016, 102(20), 1692-1692.
• Kakarla J, Parikh JD, Hollingsworth KG, Keavney B, Ford GA, O'Sullivan JJ, Blamire AM, Coats L. . In: European Society of Cardiology Congress. 2015, London, UK: Oxford University Press.
• Parikh J, Kakarla J, Hollingsworth KG, Keavney B, O'Sullivan JJ, Ford GA, Blamire AM, Coats L. . In: 18th Annual Society of Cardiovascular Magnetic Resonance Sessions. 2015, Nice, France: BioMed Central Ltd.
• Kakarla J, Coats L, Parikh JD, Hollingsworth KG, O'Sullivan J. . In: British Cardiovascular Society Annual Conference. 2014, Manchester: BMJ Group.
• Coats L, O'Connor S, Wren C, O'Sullivan J. . Heart 2014, 100(17), 1348-1353.
• Kunadian V, Coats L, Kini A, Mehran R. . Interventionals Cardiology Clinics 2012, 1(2), 231-243.
• Coats L, Runnett C, Satchithananda DK. . Cardiology in the Young 2010, 20(5), 587-589.
• Schievano S, Taylor AM, Capelli C, Coats L, Walker F, Lurz P, Nordmeyer J, Wright S, Khambadkone S, Tsang V, Carminati M, Bonhoeffer P. . EuroIntervention 2010, 5(6), 745-750.
• Vismara R, Laganà K, Migliavacca F, Schievano S, Coats L, Taylor A, Bonhoeffer P. . Artificial Organs 2009, 33(1), 46-53.
• Lurz P, Nordmeyer J, Coats L, Taylor AM, Bonhoeffer P, Schulze-Neick I. . Heart 2009, 95(8), 646-650.
• Ghez O, Tsang VT, Frigiola A, Coats L, Taylor A, VanDoorn C, Bonhoeffer P, DeLeval M. Right ventricular outflow tract reconstruction for pulmonary regurgitation after repair of tetralogy of Fallot. Preliminary results. Eur J Cardiothorac Surg 2007, 31(4), 654-8.
• Schievano S, Coats L, Migliavacca F, Norman W, Frigiola A, Deanfield J, Bonhoeffer P, Taylor AM. Variations in right ventricular outflow tract morphology following repair of congenital heart disease: implications for percutaneous pulmonary valve implantation. J Cardiovasc Magn Reson 2007, 9(4), 687-95.
• Coats L, Khambadkone S, Sullivan ID. An unusual appearance of the right ventricle following replacement of the pulmonary valve. Cardiol Young 2006, 16(4), 403-4.
• Sridharan S, Coats L, Khambadkone S, Taylor AM, Bonhoeffer P. Images in cardiovascular medicine. Transcatheter right ventricular outflow tract intervention: the risk to the coronary circulation. Circulation 2006, 113(25), e934-5.
• Coats L, Tsang V, Khambadkone S, vanDoorn C, Cullen S, Deanfield J, deLeval MR, Bonhoeffer P. The potential impact of percutaneous pulmonary valve stent implantation on right ventricular outflow tract re-intervention. Eur J Cardiothorac Surg 2005, 27(4), 536-43.