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Staff Profile

Dr Natalie Tatum

Senior Research Associate

  • Address: Cancer Research Horizons Â鶹´«Ã½ Drug Discovery Unit
    Paul O’Gorman Building
    Medical School
    Â鶹´«Ã½
    Framlington Place
    Â鶹´«Ã½ upon Tyne
    NE2 4HH
Background

Research


Senior PDRA in the structural biology group of the Unit. My areas of expertise are drug discovery, computational chemistry and biophysics.


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Publications

  • Articles

    • Pastok MW, Tomlinson CWE, Turberville S, Butler AM, Basle A, Noble MEM, Endicott JA, Pohl E, Tatum NJ. . Structure 2024, 32(12), 2301-2315.e6.
    • Rowland RJ, Korolchuk S, Salamina M, Tatum NJ, Ault JR, Hart S, Turkenburg JP, Blaza JN, Noble MEM, Endicott JA. . Nature Communications 2024, 15(1), 6807.
    • Alblihy A, Ali R, Algethami M, Shoqafi A, Toss MS, Brownlie J, Tatum NJ, Hickson I, Moran PO, Grabowska A, Jeyapalan JN, Mongan NP, Rakha EA, Madhusudan S. . npj Precision Oncology 2022, 6, 51.
    • Bieniek MK, Cree B, Pirie R, Horton JT, Tatum NJ, Cole DJ. . Communications Chemistry 2022, 5, 136.
    • Mesquita KA, Ali R, Doherty R, Toss MS, Miligy I, Alblihy A, Dorjsuren D, Simeonov A, Jadhav A, Wilson DM, Hickson I, Tatum NJ, Rakha EA, Madhusudan S. . Cancers 2021, 13(8), 1866.
    • Salamina M, Montefiore BC, Liu M, Wood DJ, Heath R, Ault JR, Wang L-Z, Korolchuk S, Basle A, Pastok MW, Reeks J, Tatum NJ, Sobott F, Arold ST, Pagano M, Noble MEM, Endicott JA. . Journal of Molecular Biology 2021, 433(5), 166795.
    • Lochhead PA, Tucker JA, Tatum NJ, Wang J, Oxley D, Kidger AM, Johnson VP, Cassidy MA, Gray NS, Noble MEM, Cook SJ. . Nature Communications 2020, 11(1), 1383.
    • Tatum NJ, Duarte F, Kamerlin SCL, Pohl E. . Journal of Physical Chemistry Letters 2019, 10(9), 2244-2249.
    • Wood DJ, Korolchuk S, Tatum NJ, Wang L-Z, Endicott JA, Noble MEM, Martin MP. . Cell Chemical Biology 2019, 26(1), 121-130.e5.
    • Haffez H, Chisholm DR, Tatum NJ, Valentine R, Redfern C, Pohl E, Whiting A, Przyborski S. . Bioorganic & Medicinal Chemistry 2018, 26(8), 1560-1572.
    • Tatum NJ, Liebeschuetz JW, Cole JC, Frita R, Herledan A, Baulard AR, Willand N, Pohl, E. . Organic and Biomolecular Chemistry 2017, 15(48), 10245-10255.
    • Tatum NJ, Yufit DS, Cobb SL, Coxon CR. . Journal of Fluorine Chemistry 2015, 173, 77-83.
    • Tatum NJ, Villemagne B, Willand N, Deprez B, Liebeschuetz JW, Baulard AR, Pohl E. Structural and docking studies of potent ethionamide boosters. Acta Crystallographica Section C: Crystal Structure Communications 2013, 69(11), 1243-1250.
    • Colgin N, Tatum NJ, Pohl E, Cobb SL, Sandford G. Synthesis and molecular structure of a perfluorinated pyridyl carbanion. Journal of Fluorine Chemistry 2012, 133, 33-37.

  • Book Chapter

    • Martin MP, Endicott JA, Noble MEM, Tatum NJ. . In: Methods in Enzymology. San Diego: Academic Press Inc, 2023, pp.211-234.

  • Reviews

    • Tatum NJ, Endicott JA. . Seminars in Cell and Developmental Biology 2020, 107, 4-20.
    • Lightfoot HL, Hagen T, Tatum NJ, Hall J. . FEBS Letters 2019, 593(16), 2083-2102.