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Staff Profile

Dr Celine Cano

Reader in Medicinal Chemistry

  • Telephone: +44 (0) 191 208 7060
  • Personal Website: /cancer/our-research/drug-discovery-and-pre-clinical-development/
  • Address: Cancer Research UK Â鶹´«Ã½ Drug Discovery Unit
    Â鶹´«Ã½ Centre for Cancer
    School of Natural & Environmental Sciences
    Bedson Building
    Â鶹´«Ã½
    Â鶹´«Ã½ upon Tyne
    NE1 7RU
Background

Background

Celine Cano is a Reader in Medicinal Chemistry at Â鶹´«Ã½. She graduated from the University of Poitiers, receiving her Ph.D. in 2004 for her work on the synthesis of biomolecules by 1,3-dipolar cycloadditions with carbohydrates. In 2004, she carried out post-doctoral work in the group of Professor John A. Joule at the University of Manchester working on the synthesis of analogues of cofactors of oxomolybdoenzymes. In 2005 she joined the Northern Institute for Cancer Research at Â鶹´«Ã½ as a research fellow, working on the synthesis of inhibitors of the DNA-dependent protein kinase (DNA-PK). She was appointed to a lectureship in Medicinal Chemistry at Â鶹´«Ã½ in 2008 and has since played a key role in helping to establish Â鶹´«Ã½ as an internationally recognised centre for anti-cancer drug discovery. Celine was awarded the Elsevier Reaxys 2017 Prize for Medicinal Chemistry in recognition of her research into anticancer drug discovery. 

She is the academic lead for the Medicinal Chemistry and Drug Discovery group within the School of Natural and Environmental Sciences.

Qualifications

  • 2000-2004 University of Poitiers University (France) – PhD in Organic Chemistry
  • 1999-2000 University of Poitiers (France) – MRes in Chemistry
  • 1995-1998 University of Poitiers (France) – MChem in Chemistry

Previous Positions

  • 2013-2017 Senior Lecturer, School of Chemistry, Northern Institute of Cancer Research, Â鶹´«Ã½
  • 2008-2013 Lecturer, Northern Institute of Cancer Research, Â鶹´«Ã½
  • 2005-2007 Research Fellow, Northern Institute of Cancer Research, Â鶹´«Ã½
  • 2004-2005 Research Associate, Chemistry Department, The University of Manchester

Area of Expertise

Medicinal Chemistry and Chemical Biology

Memberships

  • Fellow of the Royal Society of Chemistry.
  • Member of the British Association for Cancer Research and the European Association for Cancer Research.


ORCID iD: ;  ;  Scopus Author iD:  

Research
The medicinal chemistry team (C Cano, IR Hardcastle, M Waring) is part of the Drug Discovery Group within the Â鶹´«Ã½ Centre for Cancer. Working closely with basic cancer biologists, structural biologists, pharmacologists, imaging specialists, and clinical scientists, the overall aim of the programme is to discover novel small-molecule inhibitors of cancer targets which can be developed into new treatments for cancer patients.


Current Funding and Collaborations: 

  • 2018-2020       MRC DPFS Drug discovery award.  Lead PIs, S. Wedge (Pharmacology), C. Cano (Chemistry), M.E.M. Noble and J.A. Endicott (Structural Biology) 
  • 2015-2020       CRUK Programme Grant. Lead PIs, S. Wedge, M. Waring, M.E.M. Noble, J.A. Endicott, I. Hardcastle, and C. Cano, “The Cancer Research UK Programme for Drug Discovery at the Northern Institute for Cancer Research, Â鶹´«Ã½”
  • 2012-2017       Astex Strategic Drug Discovery Alliance (Astex Pharmaceuticals, Â鶹´«Ã½ and CRT) Lead PIs (Â鶹´«Ã½): C. Cano, J.A. Endicott, R.J. Griffin, I.R. Hardcastle, R. Maxwell, M. Waring, M.E.M. Noble and S. Wedge
Teaching

Stage 1 

  • CHY1101 Organic Chemistry Tutorials

Stage 2

  • Module leader of CHY2103 Medicinal Chemistry and Drug Design

Stage 3

  • CHY3109/CHY3110 Advanced Medicinal Chemistry (Semester 1) - Chemical Biology
  • CHY3109/CHY3110 Advanced Medicinal Chemistry (Semester 2) - Chemotherapy
  • CHY3109 Advanced Laboratory Course in Medicinal Chemistry
  • CHY3011 Research Literature projects

Stage 4

  • CHY8821 Methods in Drug Discovery
  • CHY8823 Theory and Practice of Chemotherapy
  • CHY8411 MChem lab placement

 Teaching Administration

  • Module leader for 3 modules as part of our Chemistry with Medicinal Chemistry BSc and MChem Honours degrees (CHY2103, CHY3109 and CHY3110)
  • Module leader for 1 module as part of our MSc in Drug Chemistry (CHY8823)
  • Member of the Northern Institute for Cancer Research Teaching and Training Committee (2009-present)
  • Member of the School of Chemistry Teaching and Training Committee (2014-2016)
Publications

  • Articles

    • Stewart HL, Bordoni C, Jennings CE, Al-Khawaldeh I, Martin MP, Noble RA, Phillips N, Pintar S, Prendergast L, Thomas HD, Wang L-Z, Watt JE, Wittner A, Bronowska AK, Cano C, Noble MEM, Wedge SR, Waring MJ. . Journal of Medicinal Chemistry 2026, 69(1), 533-552.
    • Al-Rawe SK, Baranov D, Bronowska AK, Cano C, Carroll MA, Waddell PG. . Crystals 2024, 14(12), 1070.
    • Miller DC, Reuillon T, Molyneux L, Blackburn T, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hardcastle I, Harnor SJ, Heptinstall A, Lochhead P, Martin MP, Martin NC, Myers S, Newell DR, Noble RA, Phillips N, Rigoreau L, Thomas H, Tucker JA, Wang L-Z, Waring MJ, Wong A-C, Wedge SR, Noble MEM, Cano C. . Journal of Medicinal Chemistry 2022, 65(9), 6513-6540.
    • Davison G, Martin MP, Turberville S, Dormen S, Heath R, Heptinstall AB, Lawson M, Miller DC, Ng YM, Sanderson JN, Hope I, Wood DJ, Cano C, Endicott JA, Hardcastle IR, Noble MEM, Waring MJ. . Journal of Medicinal Chemistry 2022, 65(22), 15416-15432.
    • Gai C, Harnor SJ, Zhang S, Cano C, Zhuang C, Zhao Q. . RSC Medicinal Chemistry 2022, 13(12), 1460-1475.
    • Chessari G, Hardcastle IR, Ahn JS, Anil B, Anscome E, Bawn RH, Bevan LD, Blackburn TJ, Buck I, Cano C, Carbain B, Castro J, Cons B, Cully SJ, St Denis J, Endicott JA, Fazal L, Golding BT, Griffin RJ, Haggerty K, Harnor S, Hearn K, Hobson S, Holvey RS, Howard S, Jennings C, Johnson CN, Lunec J, Miller DC, Newell DR, Noble MEM, Reeks J, Revill CH, Riedinger C, Tamanini E, Thomas H, Thompson NT, Vinkovic M, Wedge SR, Williams PA, Wilsher N, Zhang B, Zhao Y. . Journal of Medicinal Chemistry 2021, 64(7), 4071-4088.
    • Picazo EMH, Heptinstall AB, Wilson DM, Cano C, Golding BT, Waring MJ. . Journal of Heterocyclic Chemistry 2021, 58(4), 947-951.
    • Al-Khawaldeh I, Aldred GG, Alyassiri M, Basmadjian C, Bordoni C, Harnor SJ, Heptinstall AB, Hobson SJ, Jennings CE, Khalifa S, Lebraud H, Miller DC, Shrives HJ, de Souza JV, Stewart HL, Temple M, Totobenazara J, Tucker JA, Tudhope SJ, Wang LZ, Bronowska AK, Cano C, Endicott JA, Golding BT, Hardcastle IR, Hickson I, Wedge SR, Willmore E, Noble MEM, Waring MJ. . Journal of Medicinal Chemistry 2021, 64(14), 10001-10018.
    • Byrne MJ, Nasir N, Basmadjian C, Bhatia C, Cunnison RF, Carr KH, Mas-Droux C, Yeoh S, Cano C, Bayliss R. . Biochemical Journal 2020, 477(8), 1525-1539.
    • Ford BE, Chachra SS, Alshawi A, Brennan A, Harnor S, Cano C, Baker DJ, Smith DM, Fairclough RJ, Agius L. . Diabetes, Obesity and Metabolism 2020, 22(11), 1985-1994.
    • Matheson CJ, Coxon CR, Bayliss R, Boxall K, Carbain B, Fry AM, Hardcastle IR, Harnor SJ, Mas-Droux C, Newell DR, Richards MW, Sivaprakasam M, Turner D, Griffin RJ, Golding BT, Cano C. . RSC Medicinal Chemistry 2020, 11(6), 707-731.
    • Willoughby CE, Jiang Y, Thomas HD, Willmore E, Kyle S, Wittner A, Phillips N, Zhao Y, Tudhope SJ, Prendergast L, Junge G, Lourenco LM, Finlay MRV, Turner P, Munck JM, Griffin RJ, Rennison T, Pickles J, Cano C, Newell DR, Reeves HL, Ryan AJ, Wedge SR. . Journal of Clinical Investigation 2019, 130, 1-14.
    • Myers SM, Miller DC, Molyneux L, Arasta M, Bawn RH, Blackburn TJ, Cook SJ, Edwards N, Endicott JA, Golding BT, Griffin RJ, Hammonds T, Hardcastle IR, Harnor SJ, Heptinstall AB, Lochhead PA, Martin MP, Martin NC, Newell DR, Owen PJ, Pang LC, Reuillon T, Rigoreau LJM, Thomas HD, Tucker JA, Wang L-Z, Wong A-C, Noble MEM, Wedge SR, Cano C. . European Journal of Medicinal Chemistry 2019, 178, 530-543.
    • Wood D, Lopez-Fernandez JD, Knight LE, Al-Khawaldeh I, Gai C, Lin S, Martin MP, Miller DC, Cano C, Endicott JA, Hardcastle IR, Noble MEM, Waring MJ. . Journal of Medicinal Chemistry 2019, 62(7), 3741-3752.
    • Unterlass JE, Baslé A, Blackburn TJ, Tucker J, Turlais F, Cano C, Noble MME, Curtin NJ. . Oncotarget 2018, 9, 13139-13153.
    • Miller DC, Martin MP, Adhikari S, Brennan A, Endicott JA, Golding BT, Hardcastle IR, Heptinstall A, Hobson S, Jennings C, Molyneux L, Ng Y, Wedge SR, Noble MEM, Cano C. . Organic and Biomolecular Chemistry 2018, 16(11), 1843-1850.
    • Hill SL, Dunn M, Cano C, Harnor SJ, Hardcastle IR, Grundlingh J, Dargan PI, Wood DM, Tucker S, Bartram T, Thomas SHL. . Clinical Chemistry 2018, 64(2), 346-354.
    • Harnor S, Brennan A, Cano C. . ChemMedChem 2017, 12(12), 895-900.
    • Coxon RC, Wong C, Bayliss R, Boxall K, Carr KH, Fry AM, Hardcastle IR, Matheson CJ, Newell DR, Sivaprakasam M, Thomas H, Turner D, Yeoh S, Wang LZ, Griffin RJ, Golding BT, Cano C. . Oncotarget 2017, 8, 19089-19124.
    • Unterlass JE, Wood RJ, Basle A, Tucker J, Cano C, Noble MM, Curtin NJ. . Oncotarget 2017, 8(61), 104478-104491.
    • Harnor SJ, Brennan A, Cano C. . Medicinal Chemistry 2017, 7, 172-177.
    • Coxon C, Anscombe E, Harnor S, Martin M, Carbain B, Golding B, Hardcastle I, Harlow L, Korolchuk S, Matheson C, Newell D, Noble M, Sivaprakasam M, Tudhope SJ, Turner D, Wang L, Wedge SR, Wong C, Griffin R, Endicott J, Cano C. . Journal of Medicinal Chemistry 2017, 60, 1746-1767.
    • Cortese D, Konstantin C, Guglielmo S, Wang LZ, Golding BT, Cano C, Fruttero R. . ChemMedChem 2016, 11(6), 1705-1708.
    • Myers SM, Bawn RH, Bisset LC, Blackburn TJ, Cottyn B, Molyneux L, Wong AC, Cano C, Clegg W, Harrington RW, Leung H, Rigoreau L, Vidot S, Golding BT, Griffin RJ, Hammonds T, Newell DR, Hardcastle IR. . ACS Combinatorial Science 2016, 18(8), 444-455.
    • Reuillon T, Alhasan SF, Beale GS, Bertoli A, Brennan A, Cano C, Reeves HL, Newell DR, Golding BT, Miller DC, Griffin RJ. . Chemical Science 2016, 7(4), 2821-2826.
    • Zaytsev AV, Pickles JE, Harnor SJ, Henderson AP, Alyasiri M, Waddell PG, Cano C, Griffin RJ, Golding BT. . RSC Advances 2016, 6(59), 53955-53957.
    • Beale G, Haagensen E, Thomas H, Wang LZ, Revill C, Payne S, Golding BT, Hardcastle IR, Newell DR, Griffin RJ, Cano C. . British Journal of Cancer 2016, 115, 682-690.
    • Mitcheson DF, Bottrill AR, Carr K, Coxon CR, Cano C, Golding BT, Griffin RJ, Fry AM, Doerig C, Bayliss R, Tobin AB. . Malaria Journal 2016, 15, 535.
    • Anscombe E, Meschini E, Mora-Vidal R, Martin MP, Staunton D, Geitmann M, Danielson UH, Stanley WA, Wang LZ, Reuillon T, Golding BT, Cano C, Newell DR, Noble MEM, Wedge SR, Endicott JA, Griffin RJ. . Chemistry & Biology 2015, 22(9), 1159-1164.
    • Carbain B, Coxon CR, Lebraud H, Elliott KJ, Matheson CJ, Meschini E, Roberts AR, Turner DM, Wong C, Cano C, Griffin RJ, Hardcastle IR, Golding BT. . Chemistry: A European Journal 2014, 20(8), 2311-2317.
    • Harnor SJ, Rennison T, Galler M, Cano C, Griffin RJ, Newell DR, Golding BT. . MedChemComm 2014, 5(7), 984-988.
    • Lebraud H, Coxon CR, Archard VS, Bawn CM, Carbain B, Matheson CJ, Turner DM, Cano C, Griffin RJ, Hardcastle IR, Baisch U, Harrington RW, Golding BT. . Organic & Biomolecular Chemistry 2014, 12, 141-148.
    • Mould E, Berry P, Jamieson D, Hill C, Cano C, Tan N, Elliott S, Durkacz B, Newell D, Willmore E. . Biochemical Pharmacology 2014, 88(1), 58-65.
    • Carbain B, Paterson DJ, Anscombe E, Campbell AJ, Cano C, Echalier A, Endicott JA, Golding BT, Haggerty K, Hardcastle IR, Jewsbury PJ, Newell DR, Noble MEM, Roche C, Wang LZ, Griffin RJ. . Journal of Medicinal Chemistry 2014, 57(1), 56-70.
    • Lebraud H, Cano C, Carbain B, Hardcastle IR, Harrington RW, Griffin RJ, Golding BT. . Organic & Biomolecular Chemistry 2013, 11(11), 1874-1878.
    • Couty S, Westwood I, Kalusa A, Cano C, Travers J, Boxall K, Chow C, Burns S, Schmitt J, Pickard P, Barillari C, McAndrew C, Clarke P, Linardopoulos S, Griffin R, Aherne W, Raynaud F, Workman P, Jones K, Montfort R. . Oncotarget 2013, 4(10), 1647-1661.
    • Cano C, Saravanan K, Bailey C, Bardos J, Curtin NJ, Frigerio M, Golding BT, Hardcastle IR, Hummersone MG, Menear KA, Newell DR, Richardson CJ, Shea K, Smith GCM, Thommes P, Ting A, Griffin RJ. . Journal of Medicinal Chemistry 2013, 56(16), 6386-6401.
    • Clapham KM, Rennison T, Jones G, Craven F, Bardos J, Golding BT, Griffin RJ, Haggerty K, Hardcastle IR, Thommes P, Ting A, Cano C. . Organic & Biomolecular Chemistry 2012, 10(33), 6747-6757.
    • Tavecchio M, Munck JM, Cano C, Newell DR, Curtin NJ. . Cancer Chemotherapy and Pharmacology 2012, 69(1), 155-164.
    • Munck JM, Batey MA, Zhao Y, Jenkins H, Richardson C, Cano C, Tavecchio M, Barbeau J, Bardos J, Cornell L, Griffin RJ, Menear KA, Slade A, Thommes P, Martin NMB, Newell DR, Smith GCM, Curtin NJ. . Molecular Cancer Therapeutics 2012, 11(8), 1789-1798.
    • Rodriguez SA, Clapham KM, Barrett L, Cano C, Desage ME, Griffin RJ, Hardcastle IR, Payne SL, Rennison T, Richardson C, Golding BT. . Organic & Biomolecular Chemistry 2011, 9(17), 6066-6074.
    • Clapham KM, Bardos J, Finlay R, Golding BT, Griffen EJ, Griffin RJ, Hardcastle IR, Menear KA, Ting A, Turner P, Young GL, Cano C. . Bioorganic & Medicinal Chemistry Letters 2011, 21(3), 966-970.
    • Marchetti F, Cano C, Curtin NJ, Golding BT, Griffin RJ, Haggerty K, Newell DR, Parsons RJ, Payne SL, Wang LZ, Hardcastle IR. . Organic & Biomolecular Chemistry 2010, 8(10), 2397-2407.
    • Payne SL, Rodriguez-Aristegui S, Bardos J, Cano C, Golding BT, Hardcastle IR, Peacock M, Parveen N, Griffin RJ. . Bioorganic & Medicinal Chemistry Letters 2010, 20(12), 3649-3653.
    • Cano C, Barbeau OR, Bailey C, Cockcroft XL, Curtin NJ, Duggan H, Frigerio M, Golding BT, Hardcastle IR, Hummersone MG, Knights C, Menear KA, Newell DR, Richardson CJ, Smith GC, Spittle B, Griffin RJ. . Journal of Medicinal Chemistry 2010, 53(24), 8498-8507.
    • Cano C, Golding BT, Haggerty K, Hardcastle IR, Peacock M, Griffin RJ. . Organic & Biomolecular Chemistry 2010, 8(8), 1922-1928.
    • Willmore E, Elliott SL, Mainou-Fowler T, Summerfield GP, Jackson GH, O'Neill F, Lowe C, Carter A, Harris R, Pettitt AR, Cano-Soumillac C, Griffin RJ, Cowell IG, Austin CA, Durkacz BW. . Clinical Cancer Research 2008, 14(12), 3984-3992.
    • Murr M, Cano C, Golding BT, Hardcastle IR, Hummersome M, Frigerio M, Curtin NJ, Menear K, Richardson C, Smith G, Griffin R. . Bioorganic and Medicinal Chemistry Letters 2008, 18(17), 4885-4890.
    • Barbeau OR, Cano-Soumillac C, Griffin RJ, Hardcastle IR, Smith GCM, Richardson C, Clegg W, Harrington RW, Golding BT. . Organic & Biomolecular Chemistry 2007, 5(16), 2670-2677.
    • Hollick J, Rigoreau L, Cano-Soumillac C, Cockcroft X, Curtin NJ, Frigerio M, Golding BT, Guiard S, Hardcastle IR, Hickson I, Hummersone M, Menear K, Martin N, Matthews I, Newell DR, Ord R, Richardson C, Smith G, Griffin RJ. . Journal of Medicinal Chemistry 2007, 50(8), 1958-1972.
    • Bashiardes G, Cano C, Mauzé B. . Synlett 2005, (9), 1425-1428.
    • Bashiardes G, Cano C, Mauzé B. . Synlett 2005, (4), 587-590.
    • Alphonse F-A, Karim R, Cano-Soumillac C, Hebray M, Collison D, Garner CD, Joule JA. . Tetrahedron 2005, 61(46), 11010-11019.

  • Book Chapters

    • Cano C, Harnor SJ, Willmore E, Wedge SR. . In: Pollard J; Curtin N, ed. Targeting the DNA Damage Response for Anti-Cancer Therapy. New York: Humana Press Inc, 2018, pp.339-357.
    • Harnor S, Pickles J, Cano C. . In: Waring M, ed. Topics in Medicinal Chemistry. Springer, 2017, pp.1-38.

  • Conference Proceedings (inc. Abstracts)

    • Willmore E, Ahn M, Bevan L, Kyle S, Zhao Y, Thomas H, Rankin KS, Bevan L, Fazal L, Hearn K, Wilsher N, Kucia-Tran J, Ferrari N, Wallis N, Thompson N, Lyons J, Miller D, Cano C, Noble M, Hardcastle I, Howard S, Chessari G, Lunec J, Newell DR, Wedge S. . In: Proceedings of the American Association for Cancer Research Annual Meeting 2024. 2024, San Diego, California: AACR.
    • Ahn M, Bevan L, Buck I, Cano C, Castro J, Cons B, Endicott J, Fazal L, Ferrari N, Hardcastle I, Hearn K, Holvey R, Howard S, Johnson C, Jennings C, Kucia-Tran J, Kyle S, Lunec J, Lyons J, Miller D, Rees D, Noble M, Newell DR, Reeks J, Saini H, St Denis J, Tamanini E, Thomas H, Thompson N, Vinkovic M, Ward G, Wallis N, Walton H, Wedge S, Williams P, Willmore E, Wilshire N, Zhao Y, Chessari G. . In: American Association for Cancer Research Annual Meeting. 2024, San Diego: AACR Journals.
    • Unterlass JE, Aljufri N, Bex S, Cano C, Noble MEM, Curtin NJ. . In: AACR 106th Annual Meeting 2015. 2015, Philadelphia, PA, USA: American Association for Cancer Research.
    • Bertoli A, Adhikari S, Harnor SJ, Zhao Y, Lunec J, Wedge SR, Tudhope S, Wittner A, Golding BT, Hardcastle IR, Cano C, Newell DR, Griffin RJ. . In: 247th ACS National Meeting and Exposition. 2014, Dallas, TX, USA: American Chemical Society.
    • Tudhope S, Zhao Y, Wittner A, Wilmore E, Bertoli A, Adhikari S, Harnor SJ, Del Bello F, Piergentili A, Lunec J, Hardcastle IR, Griffin RJ, Golding BR, Cano C, Newell DR, Wedge SR. . In: AACR Annual Meeting 2014. 2014, San Diego, CA: American Association for Cancer Research.
    • Myers S, Martin N, Bawn R, Blackburn T, Barrett L, Reuillon T, Golding B, Griffin R, Hammonds T, Hardcastle I, Leung H, Newell D, Rigoreau L, Wong A, Cano C. . In: 26th EORTC – NCI – AACR Symposium on Molecular Targets and Cancer Therapeutics. 2014, Barcelona, Spain: Elsevier.
    • Lebraud H, Golding BT, Meschini E, Cano C, Anscombe E, Wang LZ, Endicott JA, Noble MEM, Newell DR, Griffin RJ. . In: 247th ACS National Meeting and Exposition. 2014, Dallas, Texas: American Chemical Society.
    • Cully SJ, Blackburn TJ, Cano C, Golding BT, Griffin RJ, Lunec J, Newell D, Noble M, Zhao Y, Hardcastle IR. . In: 245th ACS National Meeting and Exposition. 2013, New Orleans, Louisiana: American Chemical Society.
    • Barrett L, Rennison T, Clapham KM, Rodriguez-Aristegui S, Bardos J, Curtin NJ, Dennis M, Finlay R, Golding BT, Hardcastle IR, Newell DR, Young G, Cano C, Griffin RJ. . In: 245th ACS National Meeting and Exposition. 2013, New Orleans, Louisiana: American Chemical Society.
    • Myers SM, Bawn RH, Cottyn B, Golding BT, Griffin RJ, Hammonds T, Leung H, Newell D, Rigoreau L, Wong AC, Hardcastle IR, Cano C. Hit validation of ERK5 inhibitors: Expectations and challenges. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC.
    • Matheson CJ, Aherne W, Bayliss R, Boxall K, Cano C, Golding BT, Hardcastle IR, Mas-Droux C, Newell DR, Wang LZ, Griffin RJ. Design and synthesis of 8-substituted purines as inhibitors of Nek2 kinase. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2012, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC.
    • Bawn RH, Golding BT, Griffin RJ, Hammonds T, Leung H, Newell D, Rigoreau L, Wong AC, Cano C, Hardcastle IR. Development of substituted benzothiazoles as ERK5 inhibitors. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2011, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA: AMER CHEMICAL SOC.
    • Carbain B, Roche C, Endicott JA, Golding BT, Hardcastle IR, Cano C, Zhen-Wang L, Newell DR, Noble MEM, Griffin RJ. . In: European Journal of Cancer Supplements: 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. 2010, Berlin: Elsevier.
    • Clapham KM, Rennison T, Rodriguez-Aristegui S, Bardos J, Curtin NJ, Golding BT, Hardcastle IR, Newell DR, Cano C, Griffin RJ. . In: EJC Supplements: 22nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. 2010, Berlin, Germany: Pergamon.
    • Saravanan K, Albertella M, Cano C, Curtin NJ, Frigerio M, Golding BT, Haggerty K, Hardcastle IR, Hummersone M, Menear K, Newell DR, Rennison T, Richardson C, Rigoreau L, Rodriguez-Aristegui S, Smith GCM, Griffin RJ. . In: Proceedings of the 99th Annual Meeting of the American Association for Cancer Research. 2008, San Diego, CA: AACR.
    • Cano C, Curtin NJ, Golding BT, Haggerty K, Hardcastle IR, Hummersone M, Menear K, Richardson C, Smith GCM, Griffin RJ. Development of potent water-soluble inhibitors of the DNA-dependent protein kinase (DNA-PK). In: EJC SUPPLEMENTS. 2008, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND: PERGAMON-ELSEVIER SCIENCE LTD.
    • Cano C, Curtin NJ, Golding BT, Haggerty K, Hardcastle IR, Hummersone M, Menear K, Richardson C, Smith GCM, Griffin RJ. . In: 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. 2008, Geneva, Switzerland: European Journal of Cancer Supplements: Pergamon.

  • Letter

    • Guglielmo S, Cortese D, Cano C, Fruttero R. . Journal of Biomolecular Structure and Dynamics 2020, 38(13), 4016-4024.

  • Patents

    • Chessari G, Howard S, Buck IM, Cons BD, Johnson CN, Holvey RS, Rees DC, StDenis JD, Tamanini E, Golding BT, Hardcastle IR, Cano CF, Miller DC, Noble MEM, Osborne JD, Peach J, Lewis A, Hirst KL, Whittaker BP, Watson DW, Mitchell DR, Griffin RJ. . WO2017055860, 2017.
    • Chessari G, Howard S, Buck IM, Cons BD, Johnson CN, Holvey RS, Rees DC, StDenis JD, Tamanini E, Golding BT, Hardcastle IR, Cano CF, Miller DC, Noble MEM, Osborne JD, Peach J, Lewis A, Hirst KL, Whittaker BP, Watson DW, Mitchell DR, Griffin RJ. . WO/2017055859, 06/04/2017.
    • Chessari G, Howard S, Buck IM, Cons BD, Johnson CN, Holvey RS, Rees DC, St Denis JD, Tamanini E, Golding BT, Hardcastle IR, Cano CF, Miller DC, Noble MEM, Griffin RJ, Osborne JD, Peach J, Lewis A, Hirst KL, Whittaker BP, Watson DR. . PCT/GB2016/053041, 06/04/2017.
    • Reuillon T, Miller D, Myers S, Molyneux L, Cano C, Hardcastle I, Griffin R, Rigoreau L, Golding B, Noble M. . WO/2016/042341, 24/03/2016.

  • Reviews

    • Miller DC, Harnor SJ, Martin MP, Noble RA, Wedge SR, Cano C. . Journal of Medicinal Chemistry 2023, 66(7), 4491-4502.
    • Zografou-Barredo NA, Hallatt A, Goujon-Ricci J, Cano C. . Bioorganic & Medicinal Chemistry 2023, 88-89, 117334.
    • Potts AJ, Cano C, Thomas SHL, Hill SL. . Clinical Toxicology 2020, 58(2), 82-98.
    • Heptinstall AB, Adiyasa IWS, Cano C, Hardcastle IR. . Future Medicinal Chemistry 2018, 10(11), 1369–1388.
    • Cano C. . Comprehensive Heterocyclic Chemistry III: A Review of the Literature 1995-2007 2008, 4/15, 1271-1304.
    • Cano-Soumillac C. . Comprehensive Heterocyclic Chemistry III, A review of the literature 1995-2007 2008, 4/15, 1243-1270.