Fluid control leaves primates unaffected, study finds Published on: 28 September 2016 An examination of the use of fluid rewards in primates has found that the animals are largely unaffected by controlled water access. Scientists at Âé¶¹´«Ã½ report in the their findings on the effects of fluid control on primates within limits widely used worldwide, and more restrictive than normally granted nowadays in the UK. This provides the first significant scientific evidence as to whether there are potential welfare consequences - an area that has in the past been of concern. Studies often use awake, behaving primates to investigate cognitive and neural processes. These require the tasks to be repeated many times to achieve adequate data of high enough quality. Fluid control within exacting standards laid down by the Home Office can be used as a motivational factor. The scientists report on physiological and behavioural changes induced by fluid control, assessed in four primates over 16 weeks. These were compared to results when the monkeys had free access to water and where possible, to a control group at another site. The scientists found that widely used fluid control protocols did not result in physiological changes of concern to animal welfare. Similarly, there was no evidence of fluid control increasing anxiety, as measured through behaviour changes such as body shaking, self-grooming or yawning. No physiological changes Alexander Thiele, Professor of Visual Neuroscience, explained: "There were no physiological changes that could give rise to short or longer term welfare concerns. This should not be a surprise as the ecology of the primates means that in the wild they go for days without water intake. “Behavioural changes were equally very limited. While some changes suggested that welfare might be mildly compromised by water control, other even suggested the opposite." Work on primates at Âé¶¹´«Ã½ is only carried out where no suitable alternatives can be found and under the strict control of the Home Office and ethics committee. The University works to replace, reduce and refine the use of animals in research and this study was funded by the . Most research primates are macaques or marmosets. They are used in relatively small numbers and make up around 0.1% of research animals but they have been important in many important medical advances; for example the polio vaccine, life support systems for premature babies, and deep brain stimulation for Parkinson’s Disease. REFERENCE: DOI: http://dx.doi.org/10.1523/ENEURO.0195-16.2016 Share: Latest News Scientists unlock hidden driver of inflammatory bowel disease Scientists have linked a key genetic signal in inflammatory bowel disease to an immune response that shuts down inflammation control, enabling faster diagnosis and targeted treatments. published on: 15 June 2026 Funding system risks limiting genuine community collaboration A new policy paper written by researchers at Âé¶¹´«Ã½ warns that the way UK research is funded may be undermining efforts to create genuinely collaborative partnerships with communities. published on: 15 June 2026 Volunteers help turn Whitley Bay beach into maths experiment Members of the public joined mathematicians from Âé¶¹´«Ã½ to create what organisers believe is the largest aperiodic tiling ever attempted on Whitley Bay beach. published on: 15 June 2026 Facts and figures